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Edition 28 Sep 202618 medical topicsOriginal sources linked
Longevity
4 articles · Newest source date first
Preclinical study in miceLongevity ·
Semaglutide and ageing: promising mouse results need human testing
An experiment in older female mice found functional benefits and a longer lifespan.
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Preclinical aging biologyLongevity ·
Aging stem cells may drive chronic inflammation through maladaptive 'trained immunity'
New work identifies loss of the mitochondrial regulator SIRT3 in hematopoietic stem cells as a potential upstream driver of inflammaging.
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Computational network medicineLongevity ·
Network map of 2,358 longevity-linked genes identifies drug-repurposing candidates for aging biology
Researchers mapped the molecular hallmarks of aging onto the human protein interactome and screened thousands of compounds computationally.
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Longevity ·
Human calorie-restriction study identifies a possible molecular link to lower 'inflammaging'
Proteomic analysis of CALERIE participants suggests that modest long-term calorie restriction may dampen complement-related inflammatory signalling.
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