Medical language, translated into normal language.
Search the words you see in blood results, ultrasound reports, prescriptions, hospital letters and medical news. Definitions are written for patients and the public—not for an exam textbook.
Blood & Laboratory
FBC/CBC, iron studies, clotting, inflammatory markers and common laboratory terminology.
Full blood countAlso: FBC · CBC · Complete blood count
A blood test that counts red cells, white cells and platelets and reports measurements such as haemoglobin and red-cell size.
Open definition page →HaemoglobinAlso: Hemoglobin · Hb
The oxygen-carrying protein inside red blood cells. Low haemoglobin is a key feature of anaemia.
Open definition page →HaematocritAlso: Hematocrit · Hct · PCV
The proportion of blood volume made up of red blood cells.
Open definition page →Red blood cell countAlso: RBC
The number of red blood cells in a measured volume of blood.
Open definition page →White blood cell countAlso: WBC
The total number of infection- and immunity-related white blood cells.
Open definition page →Platelet countAlso: PLT
The number of platelets in blood. Platelets are essential for normal clot formation.
Open definition page →MCVAlso: Mean corpuscular volume
The average size of red blood cells. A low MCV suggests microcytosis; a high MCV suggests macrocytosis.
Open definition page →MCHAlso: Mean corpuscular haemoglobin
The average amount of haemoglobin in each red blood cell.
Open definition page →MCHCAlso: Mean corpuscular haemoglobin concentration
The average concentration of haemoglobin inside red blood cells.
Open definition page →RDWAlso: Red cell distribution width
A measure of how much red blood cells vary in size.
Open definition page →Neutrophils
White blood cells especially important in bacterial infection and acute inflammation.
Open definition page →Absolute neutrophil countAlso: ANC
The actual number of neutrophils in blood, rather than their percentage.
Open definition page →Neutropenia
A lower-than-normal neutrophil count. Infection risk rises when neutropenia becomes more severe.
Neutrophilia
A higher-than-normal neutrophil count, commonly seen with infection, inflammation, stress or corticosteroid treatment.
Open definition page →Lymphocytes
White blood cells central to adaptive immunity, including antiviral responses and antibody production.
Open definition page →Lymphocytosis
A higher-than-normal lymphocyte count, seen with some infections and blood disorders.
Open definition page →Lymphopenia
A lower-than-normal lymphocyte count, which can occur with acute illness, medicines and immune disorders.
Open definition page →Monocytes
White blood cells involved in longer-term immune responses and clearance of damaged material.
Open definition page →Eosinophils
White blood cells that can increase in allergies, asthma, parasitic infection and some drug reactions.
Open definition page →Basophils
A small group of white blood cells involved in allergic and inflammatory signalling.
Open definition page →Immature granulocytesAlso: IG
Young white blood cells released from bone marrow, often increased during strong marrow responses.
Open definition page →Left shift
A laboratory description meaning increased immature neutrophil forms are present, often during acute infection or inflammation.
Open definition page →Blood filmAlso: Peripheral smear
A blood sample spread thinly on a slide so the shape and appearance of cells can be examined under a microscope.
Open definition page →AnaemiaAlso: Anemia
A condition in which haemoglobin is too low to carry oxygen normally. Causes include iron deficiency, bleeding and chronic disease.
Open definition page →Microcytosis
Red blood cells that are smaller than usual, usually reflected by a low MCV.
Open definition page →Macrocytosis
Red blood cells that are larger than usual, usually reflected by a high MCV.
Open definition page →Hypochromia
Red blood cells containing less haemoglobin than usual, often seen with iron deficiency.
Open definition page →Anisocytosis
More variation in red-cell size than usual, often associated with a raised RDW.
Open definition page →Poikilocytosis
More variation in red-cell shape than usual.
Open definition page →Reticulocyte count
A count of young red blood cells that helps show how actively bone marrow is making new red cells.
Open definition page →Ferritin
A protein that stores iron. Low ferritin usually indicates depleted iron stores; ferritin can rise during inflammation.
Open definition page →Serum iron
The amount of circulating iron measured at one point in time. It varies and is usually interpreted with other iron studies.
Open definition page →Transferrin
A protein that transports iron in the blood.
Open definition page →Transferrin saturationAlso: TSAT
The percentage of transferrin carrying iron. It helps assess iron deficiency and iron overload.
Open definition page →TIBCAlso: Total iron-binding capacity
An estimate of how much iron the blood could carry if transferrin were fully occupied.
Open definition page →Iron deficiency
A state in which the body has insufficient iron. It can exist before haemoglobin falls enough to cause anaemia.
Open definition page →Iron-deficiency anaemia
Anaemia caused by insufficient iron for normal haemoglobin production.
Open definition page →Vitamin B12
A vitamin needed for normal blood formation and neurological function.
Open definition page →FolateAlso: Folic acid
A B vitamin required for DNA synthesis and normal blood-cell production.
Open definition page →ESRAlso: Erythrocyte sedimentation rate
A non-specific marker that can increase with inflammation, infection, autoimmune disease and other conditions.
Open definition page →CRPAlso: C-reactive protein
A liver-produced protein that rises with inflammation or infection. It is useful for trends but does not identify the cause by itself.
Open definition page →Procalcitonin
A blood marker that can rise in significant bacterial infection and sepsis, but must be interpreted clinically.
Open definition page →Blood culture
A laboratory test that looks for bacteria or fungi circulating in the bloodstream.
Open definition page →Coagulation screenAlso: Clotting screen
A group of tests used to assess parts of the blood-clotting system.
Open definition page →PTAlso: Prothrombin time
A clotting test used to assess part of the coagulation pathway and to calculate INR.
Open definition page →INRAlso: International normalised ratio
A standardised clotting measurement commonly used to monitor warfarin.
Open definition page →aPTTAlso: Activated partial thromboplastin time
A clotting test used to assess another part of the coagulation system and sometimes to monitor unfractionated heparin.
Open definition page →Fibrinogen
A blood protein converted into fibrin when a clot forms.
Open definition page →D-dimer
A fragment produced when a clot is broken down. An elevated result is non-specific and does not by itself prove thrombosis.
Open definition page →Blood group
Classification of blood based on red-cell antigens, most commonly the ABO and Rh systems.
Open definition page →Crossmatch
A compatibility test performed before selected blood transfusions.
Open definition page →HaemolysisAlso: Hemolysis
Breakdown of red blood cells. It can happen in the body or accidentally after a blood sample is collected.
Open definition page →LDHAlso: Lactate dehydrogenase
An enzyme found in many tissues that can rise when cells are damaged.
Open definition page →Haptoglobin
A protein that binds free haemoglobin. Low levels can support certain diagnoses of haemolysis.
Open definition page →Direct antiglobulin testAlso: DAT · Direct Coombs test
A test that checks whether antibodies or complement are attached to red blood cells.
Open definition page →Reference range
The interval in which most results from a defined reference population fall. A result just outside the range does not automatically mean disease.
Open definition page →Critical result
A laboratory value considered dangerous enough that rapid clinical attention may be required.
Open definition page →Specimen
The sample sent for testing, such as blood, urine, stool, swab or tissue.
Open definition page →Haemolysed sampleAlso: Hemolyzed sample
A blood sample in which red cells broke down after collection, potentially making some results unreliable.
Open definition page →Clotted sample
A blood sample that formed a clot when the requested test required unclotted blood.
Open definition page →Phlebotomy
The practice of drawing blood from a vein for testing or treatment.
Open definition page →VenepunctureAlso: Venipuncture
Insertion of a needle into a vein, most commonly to collect blood.
Open definition page →Kidney, Liver & Biochemistry
Kidney function, electrolytes, liver enzymes, acid–base balance and metabolism.
Creatinine
A waste product generated mainly from muscle metabolism. It is used to estimate kidney filtration.
Open definition page →eGFRAlso: Estimated glomerular filtration rate
An estimate of how well the kidneys filter blood, calculated from creatinine and patient characteristics.
Open definition page →Urea
A waste product formed from protein metabolism and cleared mainly by the kidneys.
Open definition page →Acute kidney injuryAlso: AKI
A sudden deterioration in kidney function occurring over hours to days.
Open definition page →Chronic kidney diseaseAlso: CKD
Long-term abnormal kidney structure or function.
Open definition page →Proteinuria
Excess protein in urine. Persistent proteinuria can be a marker of kidney disease.
Open definition page →Albuminuria
Albumin in urine above the expected level, an important marker of kidney and cardiovascular risk.
Open definition page →ACRAlso: Albumin-to-creatinine ratio
A urine test comparing albumin with creatinine to estimate albumin loss.
Open definition page →Electrolytes
Minerals in body fluids that carry electrical charge, including sodium, potassium, chloride and bicarbonate.
Open definition page →Sodium
A major blood electrolyte involved in fluid balance, nerve function and blood pressure.
Open definition page →HyponatraemiaAlso: Hyponatremia
A lower-than-normal sodium concentration. Symptoms depend on how low it is and how quickly it developed.
Open definition page →HypernatraemiaAlso: Hypernatremia
A higher-than-normal sodium concentration, often reflecting a relative shortage of body water.
Open definition page →Potassium
An electrolyte essential for normal nerve, muscle and heart electrical activity.
Open definition page →HypokalaemiaAlso: Hypokalemia
A low blood potassium level that can cause weakness and, when significant, heart-rhythm problems.
Open definition page →HyperkalaemiaAlso: Hyperkalemia
A high blood potassium level that can disturb cardiac electrical activity.
Calcium
A mineral important for bone, muscle contraction, nerve transmission and many cellular processes.
Open definition page →Corrected calcium
An estimate of calcium adjusted for albumin when total calcium is measured.
Open definition page →Ionised calciumAlso: Ionized calcium
The biologically active form of calcium circulating freely in blood.
Open definition page →Magnesium
An electrolyte involved in muscle, nerve and cardiac function.
Open definition page →Phosphate
A mineral involved in bone, energy metabolism and cell function.
Open definition page →Bicarbonate
A major blood buffer that helps maintain acid–base balance.
Open definition page →Anion gap
A calculated value from electrolytes that can help classify some disturbances of blood acidity.
Open definition page →Liver function testsAlso: LFTs
A group of tests used to assess liver-cell injury, bile flow and protein production.
Open definition page →ALTAlso: Alanine aminotransferase
A liver-enriched enzyme that often rises with liver-cell injury.
Open definition page →ASTAlso: Aspartate aminotransferase
An enzyme found in liver, muscle and other tissues that can rise with liver or muscle injury.
Open definition page →ALPAlso: Alkaline phosphatase
An enzyme found particularly in bile ducts and bone.
Open definition page →GGTAlso: Gamma-glutamyl transferase
An enzyme often used to help identify a liver or bile-duct source of abnormal liver tests.
Open definition page →Bilirubin
A yellow pigment produced when haemoglobin is broken down. High levels can cause jaundice.
Open definition page →Albumin
The main protein in blood plasma, important for fluid balance and transport of many substances.
Open definition page →Total protein
A measurement of major blood proteins, particularly albumin and globulins.
Open definition page →JaundiceAlso: Icterus
Yellowing of the skin or eyes caused by increased bilirubin.
Open definition page →Cholestasis
Reduced or obstructed flow of bile from the liver.
Open definition page →Hepatitis
Inflammation of the liver caused by infection, alcohol, medicines, autoimmune disease or other conditions.
Open definition page →SteatosisAlso: Fatty liver
Excess fat accumulation in cells, most commonly used to describe fatty liver.
Open definition page →MASLDAlso: Metabolic dysfunction-associated steatotic liver disease
The current term for fatty liver disease associated with metabolic dysfunction.
Open definition page →MASHAlso: Metabolic dysfunction-associated steatohepatitis
Metabolic fatty liver disease with liver-cell injury and inflammation.
Open definition page →Fibrosis
Formation of excess scar tissue after ongoing or repeated tissue injury.
Open definition page →Cirrhosis
Advanced scarring of the liver that distorts normal structure and can impair function.
Open definition page →Amylase
A digestive enzyme that can rise in pancreatic and some other conditions.
Open definition page →Lipase
A digestive enzyme commonly measured when pancreatitis is suspected.
Open definition page →Lactate
A substance produced during metabolism that can rise with poor tissue perfusion, severe infection, seizures and other states.
Open definition page →Acidosis
A process that makes body fluids more acidic than normal.
Open definition page →Alkalosis
A process that makes body fluids more alkaline than normal.
Open definition page →Blood gasAlso: ABG · VBG
A test measuring oxygen, carbon dioxide and acid–base status, usually from arterial or venous blood.
Open definition page →Osmolality
A measure of the concentration of dissolved particles in a fluid such as blood or urine.
Open definition page →Heart & Circulation
Blood pressure, rhythm, coronary disease, heart failure and vascular terminology.
Blood pressure
The force exerted by circulating blood against artery walls, expressed as systolic over diastolic pressure.
Open definition page →Systolic blood pressure
The upper blood-pressure number, representing arterial pressure when the heart contracts.
Open definition page →Diastolic blood pressure
The lower blood-pressure number, representing arterial pressure when the heart relaxes between beats.
Open definition page →HypertensionAlso: High blood pressure
Persistently elevated blood pressure. It often causes no symptoms but increases long-term cardiovascular and kidney risk.
Open definition page →HypotensionAlso: Low blood pressure
Blood pressure that is lower than expected. It matters mainly when it causes symptoms or reflects illness.
Open definition page →Heart rateAlso: Pulse
The number of heart beats per minute.
Open definition page →Tachycardia
A heart rate faster than expected for the situation.
Open definition page →Bradycardia
A heart rate slower than expected for the situation.
Open definition page →Palpitations
The sensation of being aware of the heartbeat, such as racing, pounding, fluttering or skipped beats.
Open definition page →Arrhythmia
An abnormal heart rhythm that may be too fast, too slow or irregular.
Open definition page →Atrial fibrillationAlso: AF · AFib
A common irregular rhythm arising in the upper chambers of the heart. It can increase stroke risk.
Open definition page →Atrial flutter
A rapid organised rhythm arising in the atria, related to but different from atrial fibrillation.
Open definition page →Ectopic beatAlso: Premature beat
An extra heartbeat occurring earlier than the next expected normal beat.
Open definition page →PVCAlso: Premature ventricular contraction · Ventricular ectopic
An extra heartbeat arising from the ventricles.
Open definition page →PACAlso: Premature atrial contraction
An extra heartbeat arising from the atria.
Open definition page →SVTAlso: Supraventricular tachycardia
A rapid heart rhythm that starts above the ventricles.
Open definition page →Ventricular tachycardiaAlso: VT
A rapid rhythm originating in the ventricles. Sustained VT can be life-threatening.
Ventricular fibrillationAlso: VF
Chaotic ventricular electrical activity that stops effective blood circulation.
Angina
Chest discomfort caused by temporary insufficient blood flow to heart muscle, usually from coronary artery disease.
Open definition page →Myocardial infarctionAlso: Heart attack · MI
Death of heart-muscle tissue caused by prolonged interruption of blood supply, most often from a blocked coronary artery.
Acute coronary syndromeAlso: ACS
Urgent conditions caused by suddenly reduced blood flow to the heart, including some heart attacks and unstable angina.
Coronary artery diseaseAlso: CAD
Narrowing or blockage of the arteries supplying the heart, usually due to atherosclerosis.
Open definition page →Atherosclerosis
Build-up of cholesterol-rich plaque in artery walls.
Open definition page →Heart failure
A syndrome in which the heart cannot pump or fill well enough to meet the body's needs without abnormal pressures.
Open definition page →Ejection fractionAlso: EF
The percentage of blood pumped out of a ventricle with each contraction, usually referring to the left ventricle.
Open definition page →Cardiomyopathy
Disease of heart muscle affecting its size, thickness, stiffness or pumping ability.
Open definition page →Myocarditis
Inflammation of heart muscle.
Open definition page →Pericarditis
Inflammation of the sac surrounding the heart.
Open definition page →Endocarditis
Infection or inflammation of the inner lining of the heart, often affecting valves.
Open definition page →Heart murmur
A sound made by turbulent blood flow through the heart. Some murmurs are harmless; others reflect valve or structural disease.
Open definition page →Valve stenosis
Narrowing of a heart valve that obstructs forward blood flow.
Open definition page →Valve regurgitation
Leakage backward through a heart valve that does not close completely.
Open definition page →Aortic stenosis
Narrowing of the aortic valve between the left ventricle and the aorta.
Open definition page →Mitral regurgitation
Leakage through the mitral valve from the left ventricle back into the left atrium.
Open definition page →Deep vein thrombosisAlso: DVT
A blood clot in a deep vein, most commonly in the leg.
Open definition page →Pulmonary embolismAlso: PE
A blockage in a lung artery, usually caused by a clot that travelled from a deep vein.
Peripheral arterial diseaseAlso: PAD
Reduced blood flow to the limbs because arteries have narrowed, usually from atherosclerosis.
Open definition page →Aneurysm
Abnormal widening or ballooning of a blood-vessel wall.
Open definition page →ECGAlso: Electrocardiogram · EKG
A recording of the heart's electrical activity using electrodes on the skin.
Open definition page →Holter monitor
A portable ECG recorder worn for hours or days to detect intermittent rhythm abnormalities.
Open definition page →Ambulatory blood pressure monitoringAlso: ABPM
A portable device that measures blood pressure repeatedly over 24 hours or longer.
Open definition page →Echocardiogram
An ultrasound examination of the heart assessing structure, valve function and pumping.
Open definition page →Cardioversion
A procedure that restores a normal heart rhythm using an electrical shock or medication.
Open definition page →Pacemaker
An implanted device that delivers electrical impulses when the heart rhythm is too slow or unreliable.
Open definition page →Stent
A small mesh tube placed inside an artery to keep it open.
Open definition page →AngioplastyAlso: PCI
A procedure that widens a narrowed artery using a balloon, often followed by a stent.
Open definition page →Endocrine, Diabetes & Metabolism
Diabetes, thyroid, adrenal hormones, reproductive hormones and metabolic health.
Diabetes mellitus
A group of conditions in which blood glucose is persistently too high because insulin is absent, insufficient or not working effectively.
Open definition page →Type 1 diabetes
An autoimmune form of diabetes in which pancreatic beta cells are destroyed and insulin replacement is required.
Open definition page →Type 2 diabetes
Diabetes driven mainly by insulin resistance together with progressive failure of insulin production.
Open definition page →Prediabetes
Blood glucose higher than normal but below the usual diagnostic threshold for diabetes.
Open definition page →Insulin
A hormone that helps glucose move from blood into cells and regulates metabolism.
Open definition page →Insulin resistance
A state in which body tissues respond less effectively to insulin.
Open definition page →HyperglycaemiaAlso: Hyperglycemia
Blood glucose that is higher than normal.
Open definition page →HypoglycaemiaAlso: Hypoglycemia
Blood glucose that is too low. Severe hypoglycaemia can cause seizures or unconsciousness.
Diabetic ketoacidosisAlso: DKA
A dangerous metabolic emergency caused by severe insulin deficiency, with high ketones and blood acidity.
Hyperosmolar hyperglycaemic stateAlso: HHS
A severe diabetic emergency with extreme hyperglycaemia, dehydration and high blood osmolality.
Ketones
Chemicals produced when the body burns fat for energy. They can become dangerously high in diabetic ketoacidosis.
Open definition page →C-peptide
A substance released with the body's own insulin and used to estimate endogenous insulin production.
Open definition page →HbA1cAlso: A1c · Glycated haemoglobin
A blood test estimating average glucose exposure over roughly the previous 2–3 months.
Open definition page →Fasting glucose
Blood glucose measured after a specified period without food.
Open definition page →Random glucose
A blood glucose measurement taken without requiring fasting.
Open definition page →Thyroid gland
A gland in the neck that produces hormones regulating metabolism and many body functions.
Open definition page →TSHAlso: Thyroid-stimulating hormone
A pituitary hormone that stimulates the thyroid and is commonly the first test used to assess thyroid function.
Open definition page →Free T4Also: FT4
The unbound circulating form of thyroxine, one of the main thyroid hormones.
Open definition page →Free T3Also: FT3
The unbound circulating form of triiodothyronine.
Open definition page →Hypothyroidism
Underactivity of the thyroid gland, causing insufficient thyroid hormone.
Open definition page →Hyperthyroidism
Excess thyroid hormone production or release.
Open definition page →Hashimoto thyroiditis
An autoimmune disease that attacks the thyroid and commonly leads to hypothyroidism.
Open definition page →Graves disease
An autoimmune condition in which antibodies stimulate the thyroid and cause hyperthyroidism.
Open definition page →Thyroid nodule
A discrete lump within the thyroid gland. Most thyroid nodules are benign.
Open definition page →GoitreAlso: Goiter
Enlargement of the thyroid gland.
Open definition page →Cortisol
A steroid hormone produced by the adrenal glands that helps regulate stress response, blood pressure, glucose and inflammation.
Open definition page →Cushing syndrome
A condition caused by prolonged excessive cortisol exposure.
Open definition page →Addison disease
Primary adrenal failure causing insufficient cortisol and often aldosterone.
Open definition page →Adrenal insufficiency
Insufficient production of adrenal steroid hormones, especially cortisol.
Open definition page →ACTHAlso: Adrenocorticotropic hormone
A pituitary hormone that stimulates the adrenal glands to produce cortisol.
Open definition page →Testosterone
The main androgen hormone in men and an important hormone in women, influencing sexual function, muscle, bone and red-cell production.
Open definition page →OestradiolAlso: Estradiol
The main biologically active oestrogen during reproductive years.
Open definition page →FSHAlso: Follicle-stimulating hormone
A pituitary hormone involved in ovarian follicle development and sperm production.
Open definition page →LHAlso: Luteinising hormone · Luteinizing hormone
A pituitary hormone involved in ovulation and testosterone production.
Open definition page →Prolactin
A pituitary hormone best known for stimulating milk production.
Open definition page →Growth hormoneAlso: GH
A pituitary hormone involved in growth and metabolism.
Open definition page →IGF-1Also: Insulin-like growth factor 1
A growth factor produced mainly in response to growth hormone.
Open definition page →Metabolic syndrome
A cluster of central obesity, abnormal glucose, raised blood pressure and abnormal lipids that increases cardiovascular and diabetes risk.
Open definition page →Body mass indexAlso: BMI
Weight in kilograms divided by height in metres squared. It is a screening measure, not a direct measurement of body fat.
Open definition page →Obesity
Excess body fat that increases the risk of health problems.
Open definition page →Visceral fat
Fat stored around internal abdominal organs and strongly associated with metabolic risk.
Open definition page →Osteoporosis
A condition in which bones become less dense and structurally weaker, increasing fracture risk.
Open definition page →Osteopenia
Bone mineral density lower than expected but not low enough to meet the standard definition of osteoporosis.
Open definition page →Vitamin D
A hormone-like vitamin important for calcium balance and bone health.
Open definition page →Parathyroid hormoneAlso: PTH
A hormone that helps regulate calcium and phosphate levels.
Open definition page →Digestive System & Liver
Stomach, bowel, gallbladder, pancreas and liver conditions and procedures.
Dyspepsia
Upper abdominal discomfort or indigestion, often including fullness, burning, belching or nausea.
Open definition page →Gastro-oesophageal reflux diseaseAlso: GERD · GORD · Acid reflux
Repeated reflux of stomach contents into the oesophagus causing symptoms or complications.
Open definition page →OesophagitisAlso: Esophagitis
Inflammation of the oesophagus.
Open definition page →Gastritis
Inflammation of the stomach lining.
Open definition page →Peptic ulcer
An open sore in the lining of the stomach or first part of the small intestine.
Open definition page →Helicobacter pyloriAlso: H. pylori
A bacterium associated with gastritis, ulcers and increased gastric-cancer risk.
Open definition page →Dysphagia
Difficulty swallowing.
Open definition page →Odynophagia
Pain when swallowing.
Open definition page →HaematemesisAlso: Hematemesis
Vomiting blood.
MelaenaAlso: Melena
Black, tar-like stool caused by digested blood, usually from upper gastrointestinal bleeding.
HaematocheziaAlso: Hematochezia
Passage of fresh red or maroon blood from the rectum.
Open definition page →Constipation
Infrequent, difficult or incomplete bowel movements, often with hard stool.
Open definition page →DiarrhoeaAlso: Diarrhea
Loose or watery stools occurring more often than usual.
Open definition page →Irritable bowel syndromeAlso: IBS
A disorder of gut–brain interaction causing recurrent abdominal pain associated with altered bowel habits.
Open definition page →Inflammatory bowel diseaseAlso: IBD
A group of chronic inflammatory bowel diseases, mainly Crohn disease and ulcerative colitis.
Open definition page →Crohn disease
A chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract.
Open definition page →Ulcerative colitis
A chronic inflammatory bowel disease involving the colon, usually beginning in the rectum.
Open definition page →Diverticulosis
Presence of small outpouchings in the wall of the colon.
Open definition page →Diverticulitis
Inflammation or infection involving one or more diverticula in the colon.
Open definition page →Coeliac diseaseAlso: Celiac disease
An autoimmune condition triggered by gluten in genetically susceptible people, causing small-intestinal injury.
Open definition page →Lactose intolerance
Reduced ability to digest lactose, often causing bloating, gas and diarrhoea.
Open definition page →GallstoneAlso: Cholelithiasis
A solid deposit formed in the gallbladder.
Open definition page →Cholecystitis
Inflammation of the gallbladder, commonly caused by a gallstone blocking the cystic duct.
Open definition page →Biliary colic
Episodic upper abdominal pain caused when a gallstone temporarily obstructs bile flow.
Open definition page →Common bile duct stoneAlso: Choledocholithiasis
A gallstone located in the main bile duct.
Open definition page →Cholangitis
Infection and inflammation of the bile ducts, often due to obstruction.
Pancreatitis
Inflammation of the pancreas. Causes include gallstones, alcohol, very high triglycerides and some medicines.
Open definition page →Appendicitis
Inflammation of the appendix, usually causing progressive abdominal pain and requiring prompt assessment.
Open definition page →Peritonitis
Inflammation of the lining of the abdominal cavity, often due to infection or leakage from an abdominal organ.
Ascites
Abnormal accumulation of fluid inside the abdominal cavity.
Open definition page →Hepatomegaly
Enlargement of the liver.
Open definition page →Splenomegaly
Enlargement of the spleen.
Open definition page →Portal hypertension
Abnormally high pressure in the portal venous system, most commonly due to cirrhosis.
Open definition page →Oesophageal varicesAlso: Esophageal varices
Enlarged veins in the oesophagus caused by portal hypertension that can bleed severely.
Open definition page →Hepatic encephalopathy
Brain dysfunction caused by severe liver failure or portal-systemic shunting, leading to confusion and altered consciousness.
Open definition page →Colonoscopy
Examination of the colon with a flexible camera inserted through the rectum.
Open definition page →GastroscopyAlso: Upper endoscopy · OGD
Examination of the oesophagus, stomach and duodenum with a flexible camera passed through the mouth.
Open definition page →Respiratory
Breathing symptoms, asthma, COPD, infection, sleep apnoea and lung-function testing.
DyspnoeaAlso: Dyspnea · Shortness of breath
The sensation of difficult or uncomfortable breathing.
Open definition page →Hypoxia
Insufficient oxygen reaching body tissues.
Open definition page →HypoxaemiaAlso: Hypoxemia
Lower-than-normal oxygen concentration in arterial blood.
Open definition page →Oxygen saturationAlso: SpO2
The percentage of haemoglobin carrying oxygen, commonly estimated by a pulse oximeter.
Open definition page →Asthma
A chronic inflammatory airway disease causing variable wheeze, cough, chest tightness and breathlessness.
Open definition page →COPDAlso: Chronic obstructive pulmonary disease
A chronic lung disease with persistent airflow limitation, most often related to long-term smoking exposure.
Open definition page →Emphysema
Destruction and enlargement of small air spaces in the lungs, reducing effective gas exchange.
Open definition page →Chronic bronchitis
A clinical pattern of chronic productive cough, commonly associated with smoking and COPD.
Open definition page →Bronchitis
Inflammation of the large airways. Acute bronchitis is commonly viral.
Open definition page →Pneumonia
Infection of lung tissue causing inflammation and filling of air spaces.
Open definition page →PleurisyAlso: Pleuritis
Inflammation of the membranes around the lungs, often causing sharp pain that worsens with breathing.
Open definition page →Pleural effusion
Abnormal fluid collecting between the lung and chest wall.
Open definition page →PneumothoraxAlso: Collapsed lung
Air in the pleural space causing partial or complete lung collapse.
Pulmonary oedemaAlso: Pulmonary edema
Fluid accumulation in the lungs, often due to heart failure but also caused by other conditions.
Sleep apnoeaAlso: Sleep apnea
Repeated episodes in which breathing stops or becomes markedly reduced during sleep.
Open definition page →Obstructive sleep apnoeaAlso: OSA
Sleep apnoea caused by repeated collapse of the upper airway during sleep.
Open definition page →CPAP
A machine that provides continuous positive airway pressure through a mask to keep the airway open during sleep.
Open definition page →Spirometry
A breathing test measuring how much air a person can exhale and how quickly.
Open definition page →FEV1
The amount of air forcefully exhaled in the first second of a spirometry manoeuvre.
Open definition page →FVCAlso: Forced vital capacity
The total amount of air forcefully exhaled after taking the deepest possible breath.
Open definition page →Bronchodilator
A medicine that relaxes airway smooth muscle and makes breathing easier.
Open definition page →Inhaled corticosteroidAlso: ICS
An anti-inflammatory medicine delivered into the airways, commonly used for asthma.
Open definition page →NebuliserAlso: Nebulizer
A device that converts liquid medication into a fine mist that can be inhaled.
Open definition page →TuberculosisAlso: TB
An infection caused by Mycobacterium tuberculosis, most commonly affecting the lungs.
Open definition page →Latent tuberculosis infectionAlso: LTBI
A state in which TB bacteria are present but controlled by the immune system, without contagious active disease.
Open definition page →Pulmonary function testsAlso: PFTs
A group of tests assessing airflow, lung volumes and sometimes gas transfer.
Open definition page →Peak flow
A simple measure of the maximum speed of forced expiration, often used in asthma monitoring.
Open definition page →Neurology
Stroke, seizures, neuropathy, migraine, dementia and nervous-system terminology.
StrokeAlso: Cerebrovascular accident · CVA
Sudden brain injury caused by interruption of blood supply or bleeding in the brain.
Ischaemic strokeAlso: Ischemic stroke
Stroke caused by blockage of an artery supplying the brain.
Open definition page →Haemorrhagic strokeAlso: Hemorrhagic stroke
Stroke caused by bleeding into or around the brain.
Open definition page →TIAAlso: Transient ischaemic attack · Mini-stroke
Temporary neurological symptoms caused by transient loss of blood flow to part of the brain.
Seizure
A sudden episode of abnormal electrical activity in the brain that can alter movement, awareness, sensation or behaviour.
Open definition page →Epilepsy
A neurological condition characterised by a tendency to have recurrent unprovoked seizures.
Open definition page →Status epilepticus
A prolonged seizure or repeated seizures without adequate recovery, requiring urgent treatment.
SyncopeAlso: Fainting
A brief loss of consciousness caused by temporary reduction in blood flow to the brain, followed by spontaneous recovery.
Open definition page →Vertigo
The sensation that you or the environment is spinning or moving when it is not.
Open definition page →Dizziness
A broad symptom that may describe light-headedness, imbalance, vertigo or a feeling of impending faint.
Open definition page →Migraine
A neurological disorder causing recurrent headache attacks, often with nausea, light sensitivity and sometimes aura.
Open definition page →Aura
A temporary neurological symptom that can occur before or during some migraines or seizures.
Open definition page →Neuropathy
Damage or dysfunction of nerves outside the brain and spinal cord, often causing numbness, tingling, pain or weakness.
Open definition page →Peripheral neuropathy
Neuropathy affecting peripheral nerves, commonly beginning in the hands or feet.
Open definition page →Radiculopathy
Symptoms caused by irritation or compression of a spinal nerve root.
Open definition page →Sciatica
Pain radiating along the sciatic nerve pathway, usually from lower-back nerve-root irritation.
Open definition page →ParaesthesiaAlso: Paresthesia
Abnormal skin sensations such as pins-and-needles, tingling or burning.
Open definition page →Ataxia
Poor coordination or balance caused by dysfunction of the nervous system.
Open definition page →Tremor
Involuntary rhythmic shaking of a body part.
Open definition page →Parkinson disease
A progressive neurological disorder affecting movement and other brain functions, associated with loss of dopamine-producing neurons.
Open definition page →Dementia
A syndrome of progressive cognitive decline severe enough to interfere with independent daily functioning.
Open definition page →Alzheimer disease
The most common cause of dementia, associated with progressive impairment of memory and other cognitive functions.
Open definition page →Delirium
An acute, fluctuating disturbance of attention and thinking, usually caused by an underlying medical problem, medicine or substance.
Multiple sclerosisAlso: MS
An immune-mediated disease in which inflammation damages myelin in the central nervous system.
Open definition page →Meningitis
Inflammation of the membranes surrounding the brain and spinal cord, commonly caused by infection.
Encephalitis
Inflammation of brain tissue, often due to infection or autoimmune disease.
Aphasia
Impaired ability to understand or produce language because of brain dysfunction.
Open definition page →Dysarthria
Difficulty speaking clearly because the muscles used for speech are weak or poorly coordinated.
Open definition page →Hemiparesis
Weakness affecting one side of the body.
Open definition page →Paralysis
Loss of voluntary muscle movement in part of the body.
Open definition page →Neuralgia
Pain arising from irritation or damage to a nerve.
Open definition page →EEGAlso: Electroencephalogram
A test that records electrical activity of the brain using scalp electrodes.
Open definition page →Lumbar punctureAlso: Spinal tap
A procedure in which a needle is inserted into the lower back to collect cerebrospinal fluid or measure pressure.
Open definition page →Mental Health & Substance Use
Anxiety, depression, psychosis, sleep, dependence, withdrawal and overdose language.
Anxiety
A state of apprehension or fear that can become a disorder when persistent, excessive and impairing.
Open definition page →Generalised anxiety disorderAlso: GAD
Persistent excessive worry about multiple areas of life that is difficult to control.
Open definition page →Panic attack
A sudden surge of intense fear or discomfort with symptoms such as palpitations, breathlessness, chest tightness or dizziness.
Open definition page →Panic disorder
Recurrent unexpected panic attacks together with persistent concern or behavioural change related to further attacks.
Open definition page →Depression
A mental health condition involving persistent low mood or loss of interest together with changes in energy, sleep, appetite and functioning.
Open definition page →Major depressive disorderAlso: MDD
A clinical depressive illness meeting defined criteria for severity, duration and functional impact.
Open definition page →Bipolar disorder
A mood disorder characterised by episodes of depression and episodes of mania or hypomania.
Open definition page →Mania
A period of abnormally elevated or irritable mood with increased energy, reduced need for sleep and major behavioural change.
Open definition page →Hypomania
A milder form of elevated or irritable mood and increased energy that is less severe than mania.
Open definition page →Psychosis
Loss of contact with reality, which may include hallucinations, delusions or severely disorganised thinking.
Open definition page →Hallucination
A perception such as hearing or seeing something without an external stimulus.
Open definition page →Delusion
A fixed false belief maintained despite strong evidence to the contrary and not explained by cultural context.
Open definition page →Schizophrenia
A chronic psychiatric disorder that can involve psychosis, cognitive difficulties and functional impairment.
Open definition page →Obsessive-compulsive disorderAlso: OCD
A condition involving intrusive unwanted thoughts and repetitive behaviours or mental rituals performed to reduce distress.
Open definition page →Post-traumatic stress disorderAlso: PTSD
A trauma-related disorder that can include intrusive memories, avoidance and heightened arousal.
Open definition page →ADHDAlso: Attention-deficit/hyperactivity disorder
A neurodevelopmental condition involving persistent inattention and/or hyperactivity-impulsivity that affects daily functioning.
Open definition page →Autism spectrum disorderAlso: ASD · Autism
A neurodevelopmental condition involving differences in social communication and patterns of behaviour, interests or sensory processing.
Open definition page →Insomnia
Persistent difficulty falling asleep, staying asleep or obtaining restorative sleep despite adequate opportunity.
Open definition page →Dependence
A state in which the body adapts to a substance and stopping it may produce withdrawal. It is not identical to addiction.
Open definition page →Addiction
A substance-use or behavioural disorder characterised by impaired control, craving and continued use despite harm.
Open definition page →Tolerance
A state in which a larger dose is needed to achieve an effect previously produced by a smaller dose.
Open definition page →Withdrawal
Physical or psychological symptoms that occur when a substance is reduced or stopped after adaptation.
Open definition page →Alcohol withdrawal
Symptoms after abrupt reduction of heavy or dependent alcohol use, ranging from tremor to seizures or delirium.
Delirium tremensAlso: DTs
A severe form of alcohol withdrawal with confusion, agitation and autonomic overactivity.
Opioid
A class of medicines and drugs acting on opioid receptors, including morphine, oxycodone, fentanyl and heroin.
Open definition page →Naloxone
A medicine that rapidly reverses opioid effects and can restore breathing during an opioid overdose.
Open definition page →Overdose
Exposure to a drug or substance at a level that causes serious toxic effects.
BenzodiazepineAlso: BZD
A class of sedative medicines used for selected conditions such as acute anxiety, seizures or muscle spasm.
Open definition page →Antidepressant
A medicine used to treat depression and several anxiety-related conditions.
Open definition page →Antipsychotic
A medicine used primarily to treat psychosis, mania and some other psychiatric conditions.
Open definition page →Psychotherapy
Structured psychological treatment using evidence-based talking and behavioural approaches.
Open definition page →Cognitive behavioural therapyAlso: CBT
A form of psychotherapy focusing on links between thoughts, emotions and behaviours.
Open definition page →Suicidal ideation
Thoughts about suicide or ending one's life.
Self-harm
Deliberate injury to oneself, with or without suicidal intent.
Infection, Immunity & Autoimmune Disease
Microbiology, allergy, autoimmunity and targeted immune treatments.
Infection
Invasion and multiplication of microorganisms in the body, with or without symptoms.
Open definition page →Bacterial infection
An infection caused by bacteria.
Open definition page →Viral infection
An infection caused by a virus.
Open definition page →Fungal infection
An infection caused by fungi such as yeasts or moulds.
Open definition page →Parasitic infection
An infection caused by parasites such as protozoa or worms.
Open definition page →Pathogen
A microorganism or infectious agent capable of causing disease.
Open definition page →ColonisationAlso: Colonization
Presence of microorganisms on or in the body without causing tissue invasion or illness.
Open definition page →Contagious
Able to spread from one person to another, directly or indirectly.
Open definition page →Incubation period
The time between exposure to an infectious agent and development of symptoms.
Open definition page →Sepsis
Life-threatening organ dysfunction caused by a dysregulated response to infection.
Septic shock
A severe form of sepsis with profound circulatory and metabolic abnormalities.
BacteraemiaAlso: Bacteremia
Presence of bacteria in the bloodstream.
Open definition page →ViraemiaAlso: Viremia
Presence of virus in the bloodstream.
Open definition page →Culture
A laboratory method that allows microorganisms from a specimen to grow so they can be identified.
Open definition page →Sensitivity testingAlso: Susceptibility testing
Testing that determines which antimicrobial medicines are likely to work against a microorganism.
Open definition page →Antibiotic resistance
The ability of bacteria to survive or grow despite an antibiotic that would normally inhibit them.
Open definition page →PCRAlso: Polymerase chain reaction
A molecular laboratory technique that detects specific genetic material.
Open definition page →Antigen
A substance recognised by the immune system, often part of a microorganism or toxin.
Open definition page →AntibodyAlso: Immunoglobulin
A protein produced by B cells that recognises a specific antigen.
Open definition page →Serology
Blood testing that looks for antibodies, antigens or other markers of infection or immunity.
Open definition page →Immunity
The body's ability to recognise and defend against specific threats.
Open definition page →Innate immunity
Rapid, non-specific immune defence present from birth.
Open definition page →Adaptive immunity
Specific immune responses that develop after exposure and can create immunological memory.
Open definition page →Autoimmune disease
A disease in which the immune system mistakenly attacks the body's own tissues.
Open definition page →Immunosuppression
Reduced immune-system activity caused by disease or medication.
Open definition page →Immunodeficiency
A state in which part of the immune system is absent or does not function adequately.
Open definition page →Allergy
An immune reaction to a substance that is usually harmless to most people.
Open definition page →Anaphylaxis
A severe, rapidly developing systemic allergic reaction that can affect breathing and circulation.
UrticariaAlso: Hives
Raised itchy wheals on the skin, commonly called hives.
Open definition page →Angioedema
Deeper swelling beneath the skin, often affecting lips, eyelids or tongue.
Rheumatoid arthritisAlso: RA
A chronic autoimmune inflammatory disease that primarily attacks joints and can affect other organs.
Open definition page →Systemic lupus erythematosusAlso: SLE · Lupus
An autoimmune disease that can affect skin, joints, kidneys, blood cells, nervous system and other organs.
Open definition page →Psoriatic arthritis
Inflammatory arthritis associated with psoriasis.
Open definition page →Ankylosing spondylitisAlso: Axial spondyloarthritis
A chronic inflammatory disease primarily affecting the spine and sacroiliac joints.
Open definition page →Sjögren syndromeAlso: Sjogren syndrome
An autoimmune disorder commonly causing dry eyes and dry mouth and sometimes systemic disease.
Open definition page →Vasculitis
Inflammation of blood-vessel walls that can reduce blood flow and damage organs.
Open definition page →ANAAlso: Antinuclear antibody
A group of autoantibodies directed against cell nuclei. A positive ANA is not by itself a diagnosis.
Open definition page →Rheumatoid factorAlso: RF
An antibody that can be present in rheumatoid arthritis but also occurs in other conditions and some healthy people.
Open definition page →Anti-CCP antibodyAlso: ACPA
An antibody strongly associated with rheumatoid arthritis and useful in diagnosis.
Open definition page →Complement
A group of immune proteins that help antibodies and immune cells clear pathogens and damaged cells.
Open definition page →Biologic medicineAlso: Biologic therapy
A treatment produced using biological systems, often designed to block a specific immune or inflammatory pathway.
Open definition page →JAK inhibitor
A targeted medicine that blocks Janus kinase signalling, used in several inflammatory and blood disorders.
Open definition page →Monoclonal antibody
A laboratory-produced antibody designed to bind a specific biological target.
Open definition page →Vaccination & Travel Medicine
Vaccines, immunity, malaria, rabies, travel health and outbreak terminology.
Vaccine
A biological product that trains the immune system to recognise and respond to a specific infection or toxin.
Open definition page →Vaccination
Administration of a vaccine to produce protection against disease.
Open definition page →ImmunisationAlso: Immunization
The process by which a person becomes protected against an infection, often through vaccination.
Open definition page →Primary vaccine series
The initial set of vaccine doses needed to establish protection.
Open definition page →Booster dose
An additional vaccine dose given later to strengthen or restore protection.
Open definition page →Live attenuated vaccine
A vaccine containing a weakened living microorganism, with special precautions in pregnancy and significant immunosuppression.
Open definition page →Inactivated vaccine
A vaccine containing killed organisms or components that cannot reproduce in the body.
Open definition page →mRNA vaccine
A vaccine that delivers messenger RNA instructions so cells briefly make an antigen that stimulates immunity.
Open definition page →Conjugate vaccine
A vaccine in which a bacterial polysaccharide is linked to a protein to create a stronger immune response.
Open definition page →Toxoid vaccine
A vaccine protecting against a bacterial toxin using an inactivated form of that toxin.
Open definition page →Adjuvant
An ingredient added to some vaccines to strengthen or shape the immune response.
Open definition page →Contraindication
A condition or circumstance in which a treatment or vaccine should not be used because risk is unacceptable.
Open definition page →Precaution
A condition requiring individual clinical judgement before treatment or vaccination.
Open definition page →Adverse event
Any medical event occurring after treatment or vaccination, whether or not the treatment caused it.
Open definition page →Vaccine side effect
An unwanted effect reasonably attributable to a vaccine, such as injection-site pain or temporary fever.
Open definition page →Herd immunity
Reduced spread of an infection when a sufficiently large proportion of a population is immune.
Open definition page →Catch-up vaccination
Vaccination given to bring someone up to date after missing routine doses.
Open definition page →Seroconversion
Development of detectable antibodies after infection or vaccination.
Open definition page →Vaccine efficacy
How well a vaccine reduces disease under controlled study conditions.
Open definition page →Vaccine effectiveness
How well a vaccine works in real-world use.
Open definition page →Travel vaccine
A vaccine recommended or required because of infection risks associated with travel.
Open definition page →Yellow fever certificateAlso: International Certificate of Vaccination or Prophylaxis
Official proof of yellow fever vaccination used for specified international travel requirements.
Open definition page →Malaria prophylaxisAlso: Antimalarial prophylaxis · Chemoprophylaxis
Medication taken before, during and after travel to reduce malaria risk.
Open definition page →Traveller's diarrhoeaAlso: Traveler's diarrhea
Acute diarrhoea occurring during or shortly after travel, most often from contaminated food or water.
Open definition page →Rabies post-exposure prophylaxisAlso: Rabies PEP
Urgent treatment after a possible rabies exposure, involving wound care, vaccine and sometimes rabies immunoglobulin.
Pre-exposure prophylaxisAlso: PrEP
Preventive treatment given before a possible future exposure.
Open definition page →Endemic
Consistently present in a particular population or geographic area.
Open definition page →Epidemic
Occurrence of disease above what is normally expected in a community or region.
Open definition page →Pandemic
An epidemic that spreads across multiple countries or continents and affects large numbers of people.
Open definition page →Vector
An organism, such as a mosquito or tick, that transmits an infectious agent between hosts.
Open definition page →Vector-borne disease
An infection transmitted by organisms such as mosquitoes, ticks, fleas or sandflies.
Open definition page →Altitude sicknessAlso: Acute mountain sickness
Illness caused by inadequate acclimatisation to high altitude.
Open definition page →Jet lag
Temporary sleep and circadian disturbance after rapidly crossing multiple time zones.
Open definition page →Cancer & Oncology
Cancer diagnosis, staging, biomarkers, treatment, trials and outcome terminology.
Cancer
A group of diseases in which abnormal cells grow uncontrollably and can invade nearby tissue or spread elsewhere.
Open definition page →TumourAlso: Tumor
An abnormal mass of tissue caused by excessive or abnormal cell growth. A tumour can be benign or malignant.
Open definition page →Benign
Not cancerous. A benign growth does not invade or metastasise, although size or location can still cause problems.
Open definition page →Malignant
Cancerous, with the ability to invade surrounding tissue and potentially spread to distant sites.
Open definition page →Neoplasm
An abnormal new growth of tissue. Neoplasms can be benign, pre-malignant or malignant.
Open definition page →Metastasis
Spread of cancer cells from the original site to another part of the body.
Open definition page →Primary cancer
The organ or tissue where a cancer began.
Open definition page →Secondary cancerAlso: Metastatic cancer
Cancer present in another site because it spread from the primary cancer.
Open definition page →Carcinoma
Cancer arising from epithelial cells that line surfaces and organs.
Open definition page →Adenocarcinoma
A carcinoma arising from gland-forming epithelial cells.
Open definition page →Squamous cell carcinomaAlso: SCC
A cancer arising from squamous epithelial cells.
Open definition page →Sarcoma
A cancer arising from connective or supporting tissues such as bone, muscle or fat.
Open definition page →Lymphoma
A cancer arising from lymphocytes and lymphatic tissues.
Open definition page →LeukaemiaAlso: Leukemia
A group of cancers involving blood-forming tissues and abnormal blood cells.
Open definition page →Myeloma
A cancer of plasma cells, most commonly multiple myeloma.
Open definition page →Biopsy
Removal of a tissue or cell sample for microscopic and sometimes molecular examination.
Open definition page →Histology
Microscopic examination of tissue structure to diagnose disease.
Open definition page →Cytology
Examination of individual cells or small groups of cells under a microscope.
Open definition page →Pathology report
The formal laboratory report describing findings from tissue, cells or other specimens.
Open definition page →Grade
A description of how abnormal cancer cells look and, in many cancers, how aggressively they may behave.
Open definition page →Stage
A description of how far a cancer has spread in the body.
Open definition page →TNM stagingAlso: TNM
A cancer-staging system describing the primary tumour, regional lymph nodes and distant metastasis.
Open definition page →In situ
Abnormal or malignant cells confined to their original layer without invasion.
Open definition page →Invasive cancer
Cancer that has grown beyond the tissue layer or structure where it first developed.
Open definition page →Lymph node
A small immune-system structure that filters lymphatic fluid. Nodes can enlarge because of infection, inflammation or cancer.
Open definition page →Remission
A period in which signs and symptoms of cancer are reduced or disappear. Remission is not always the same as cure.
Open definition page →Complete responseAlso: Complete remission
Disappearance of all measurable evidence of cancer using the assessment methods being applied.
Open definition page →Partial response
A substantial reduction in measurable tumour burden that does not meet criteria for complete response.
Open definition page →Progression
Growth or spread of cancer despite or after treatment.
Open definition page →Recurrence
Return of cancer after a period in which it was undetectable or controlled.
Open definition page →Chemotherapy
Medicines that damage or kill rapidly dividing cells. Many regimens affect cancer cells and some normal cells.
Open definition page →RadiotherapyAlso: Radiation therapy
Treatment using ionising radiation to damage cancer cells.
Open definition page →Immunotherapy
Treatment that modifies or uses the immune system to attack cancer or other disease.
Open definition page →Targeted therapy
Treatment designed to interfere with a specific molecule or pathway important to a cancer.
Open definition page →Hormone therapy
Treatment that blocks or alters hormones that stimulate certain cancers.
Open definition page →Checkpoint inhibitor
A cancer immunotherapy blocking inhibitory immune checkpoints such as PD-1, PD-L1 or CTLA-4.
Open definition page →CAR-T therapy
Treatment in which a patient's T cells are genetically modified to recognise and attack a chosen target.
Open definition page →Bispecific antibody
An engineered antibody designed to bind two different targets at the same time.
Open definition page →Precision medicine
Use of molecular, genetic and clinical information to choose treatment or prevention more specifically.
Open definition page →Biomarker
A measurable biological feature used to assess disease, risk, prognosis or treatment response.
Open definition page →Tumour markerAlso: Tumor marker
A substance measured in blood or tissue that can sometimes help monitor or characterise a cancer. Most are not stand-alone screening tests.
Open definition page →PSAAlso: Prostate-specific antigen
A prostate-produced protein measured in blood. It can rise with prostate cancer, benign enlargement and inflammation.
Open definition page →CEAAlso: Carcinoembryonic antigen
A tumour marker mainly used to monitor selected colorectal and other cancers rather than diagnose cancer by itself.
Open definition page →CA-125
A blood marker used mainly in evaluating and monitoring selected ovarian and other conditions. It is not specific for cancer.
Open definition page →CA 19-9
A tumour marker used in selected pancreatic and biliary cancers but not sufficiently specific to diagnose cancer by itself.
Open definition page →Minimal residual diseaseAlso: MRD
Very small numbers of cancer cells remaining after treatment that may be detectable only with sensitive tests.
Open definition page →Progression-free survivalAlso: PFS
Time during and after treatment in which a patient remains alive without the cancer becoming measurably worse.
Open definition page →Overall survivalAlso: OS
Time from a defined starting point until death from any cause.
Open definition page →Objective response rateAlso: ORR
The proportion of study participants whose tumours shrink by a predefined amount.
Open definition page →Clinical trial
A research study involving human participants that evaluates a medical intervention, diagnostic strategy or other health approach.
Open definition page →Imaging, Ultrasound & Procedures
Ultrasound language, CT/MRI/X-ray terminology and common clinical procedures.
UltrasoundAlso: Sonography
Imaging that uses high-frequency sound waves rather than ionising radiation to create pictures of internal structures.
Open definition page →Doppler ultrasound
Ultrasound used to assess movement, particularly blood flow through vessels.
Open definition page →Echogenicity
The degree to which tissue reflects ultrasound waves, determining how bright or dark it appears.
Open definition page →Hyperechoic
Brighter than surrounding tissue on ultrasound because it reflects more sound.
Open definition page →Hypoechoic
Darker than surrounding tissue on ultrasound because it reflects less sound.
Open definition page →Anechoic
Completely or nearly black on ultrasound because there are few internal echoes, as often occurs with simple fluid.
Open definition page →Lesion
A general term for an area of abnormal tissue. The word lesion does not by itself mean cancer.
Open definition page →Mass
A discrete lump or area of tissue. A mass can have many benign or malignant causes.
Open definition page →Nodule
A relatively small, rounded or defined area of tissue that differs from its surroundings.
Open definition page →Cyst
A fluid-filled or partly fluid-filled sac. Many cysts are benign.
Open definition page →Simple cyst
A cyst with typical benign imaging features such as clear fluid and a thin smooth wall.
Open definition page →Complex cyst
A cystic lesion containing internal echoes, septa, solid areas or other features requiring closer assessment.
Open definition page →Calcification
Deposit of calcium within tissue, visible on some imaging tests.
Open definition page →Shadowing
A dark ultrasound area behind a structure that strongly blocks or reflects the sound beam, such as a gallstone.
Open definition page →Acoustic enhancement
Increased brightness behind a fluid-filled structure because sound passes easily through fluid.
Open definition page →CT scanAlso: Computed tomography
Cross-sectional imaging created with X-rays and computer processing.
Open definition page →MRIAlso: Magnetic resonance imaging
Imaging using a strong magnetic field and radiofrequency signals rather than X-rays.
Open definition page →X-ray
Imaging that uses ionising radiation to create pictures, particularly useful for bones and chest structures.
Open definition page →Contrast agent
A substance given to make structures more visible on imaging.
Open definition page →Radiopaque
Able to block X-rays and therefore appear relatively white on an X-ray image.
Open definition page →Radiolucent
Allowing X-rays to pass through more easily, producing a darker appearance on X-ray.
Open definition page →Incidental finding
An abnormality discovered unexpectedly during a test performed for another reason.
Open definition page →Biopsy-guided imaging
Use of ultrasound, CT or other imaging to guide a needle accurately into a target.
Open definition page →Endoscopy
Examination of an internal surface using a flexible or rigid instrument with a camera.
Open definition page →Laparoscopy
Keyhole surgery performed through small abdominal incisions using a camera.
Open definition page →Laparotomy
Open abdominal surgery through a larger incision.
Open definition page →Local anaestheticAlso: Local anesthetic
Medicine that temporarily numbs a specific area while the patient remains conscious.
Open definition page →General anaestheticAlso: General anesthetic
Medication-induced unconsciousness used for surgery or procedures.
Open definition page →Sedation
Medication used to reduce anxiety and awareness during a procedure without necessarily causing full general anaesthesia.
Open definition page →Catheter
A flexible tube inserted into the body to drain fluid, deliver treatment or access blood vessels.
Open definition page →Cannula
A small tube inserted into a vein for fluids or medication, or into another body space for a specific procedure.
Open definition page →IVAlso: Intravenous
A route directly into a vein.
Open definition page →IM injectionAlso: Intramuscular injection
An injection delivered into muscle.
Open definition page →Subcutaneous injectionAlso: SC injection
An injection delivered into the fatty tissue just beneath the skin.
Open definition page →Sterile
Free from living microorganisms capable of causing contamination or infection.
Open definition page →Aseptic technique
Methods used to minimise contamination by microorganisms during a procedure.
Open definition page →Women's Health & Reproductive Medicine
Menstrual, fertility, pregnancy, pelvic ultrasound and menopause terminology.
Menstrual cycle
The recurring hormonal cycle that prepares the ovaries and uterus for possible pregnancy.
Open definition page →Menstruation
Shedding of the uterine lining, producing a menstrual period.
Open definition page →AmenorrhoeaAlso: Amenorrhea
Absence of menstrual periods when they would normally be expected.
Open definition page →DysmenorrhoeaAlso: Dysmenorrhea
Painful menstruation.
Open definition page →MenorrhagiaAlso: Heavy menstrual bleeding
Menstrual bleeding that is unusually heavy or prolonged.
Open definition page →Ovulation
Release of an egg from an ovary.
Open definition page →Follicle
A fluid-filled ovarian structure containing a developing egg.
Open definition page →Corpus luteum
The temporary ovarian structure formed after ovulation that produces progesterone.
Open definition page →Endometrium
The inner lining of the uterus.
Open definition page →Endometrial thickness
The measured thickness of the uterine lining, which changes with the menstrual cycle and hormonal state.
Open definition page →FibroidAlso: Leiomyoma
A benign growth of uterine smooth muscle.
Open definition page →Endometriosis
A condition in which tissue resembling the uterine lining grows outside the uterus, causing inflammation and sometimes pain or infertility.
Open definition page →Adenomyosis
Growth of endometrial-type tissue within the muscular wall of the uterus.
Open definition page →Ovarian cyst
A fluid-filled or partly fluid-filled structure in or on an ovary. Many are functional and resolve naturally.
Open definition page →Polycystic ovary syndromeAlso: PCOS
A hormonal and metabolic condition commonly associated with irregular ovulation, androgen excess and polycystic ovarian morphology.
Open definition page →Cervix
The lower part of the uterus that opens into the vagina.
Open definition page →Pap smearAlso: Pap test · Cervical cytology
A screening test collecting cervical cells to look for changes associated with cervical-cancer risk.
Open definition page →HPVAlso: Human papillomavirus
A group of viruses, some of which can cause genital warts and some of which increase the risk of cervical and other cancers.
Open definition page →Colposcopy
Close examination of the cervix using magnification after an abnormal cervical screening result or other indication.
Open definition page →Pregnancy testAlso: hCG test
A test that detects human chorionic gonadotropin, a hormone produced during pregnancy.
Open definition page →hCGAlso: Human chorionic gonadotropin
A hormone produced mainly by placental tissue during pregnancy. Levels rise rapidly in early pregnancy.
Open definition page →Gestational age
The age of a pregnancy counted from the first day of the last menstrual period.
Open definition page →Ectopic pregnancy
A pregnancy implanted outside the main cavity of the uterus, most commonly in a fallopian tube.
Miscarriage
Loss of a pregnancy before fetal viability, usually in the first half of pregnancy.
Open definition page →Placenta
The organ that develops during pregnancy to exchange oxygen, nutrients and waste products between mother and fetus.
Open definition page →Menopause
The permanent end of menstrual periods due to loss of ovarian follicular activity.
Open definition page →Perimenopause
The transition leading up to menopause, during which cycle timing and symptoms can change.
Open definition page →HRTAlso: Hormone replacement therapy · Menopausal hormone therapy
Hormonal treatment used to relieve menopausal symptoms and for selected other indications.
Open definition page →Transvaginal ultrasound
Pelvic ultrasound performed with a probe inserted gently into the vagina to obtain close views of the uterus and ovaries.
Open definition page →Transabdominal pelvic ultrasound
Pelvic ultrasound performed through the lower abdomen, usually with a full bladder to improve the view.
Open definition page →Musculoskeletal & Rheumatology
Bones, joints, tendons, arthritis, osteoporosis and common injuries.
Arthritis
Inflammation or structural disease of a joint causing pain, swelling, stiffness or reduced movement.
Open definition page →OsteoarthritisAlso: OA
A common joint disease involving cartilage loss and changes in bone and other joint tissues.
Open definition page →Synovitis
Inflammation of the membrane lining a joint.
Open definition page →Joint effusion
Excess fluid inside a joint.
Open definition page →Bursitis
Inflammation of a bursa, a small fluid-filled sac that reduces friction near joints.
Open definition page →TendinitisAlso: Tendonitis
Inflammation or irritation of a tendon.
Open definition page →Tendinopathy
A broader term for tendon pain and structural change, often related to overload rather than acute inflammation alone.
Open definition page →Ligament
A strong band of connective tissue connecting bone to bone.
Open definition page →Tendon
Strong connective tissue that attaches muscle to bone.
Open definition page →Sprain
Injury to a ligament, usually from stretching or tearing.
Open definition page →Strain
Injury to muscle or tendon.
Open definition page →Fracture
A break or crack in a bone.
Open definition page →Stress fracture
A small bone fracture caused by repeated loading rather than a single major injury.
Open definition page →Dislocation
Complete loss of normal contact between joint surfaces.
Open definition page →Subluxation
Partial loss of normal joint alignment without complete dislocation.
Open definition page →Meniscus
A crescent-shaped pad of fibrocartilage in the knee that helps distribute load and stabilise the joint.
Open definition page →ACLAlso: Anterior cruciate ligament
A major knee ligament controlling forward and rotational movement of the tibia.
Open definition page →Rotator cuff
A group of shoulder muscles and tendons that stabilise the shoulder and help lift and rotate the arm.
Open definition page →Frozen shoulderAlso: Adhesive capsulitis
Painful progressive stiffness of the shoulder capsule.
Open definition page →Carpal tunnel syndrome
Compression of the median nerve at the wrist, causing numbness, tingling and sometimes hand weakness.
Open definition page →Gout
Inflammatory arthritis caused by deposition of monosodium urate crystals in joints.
Open definition page →PseudogoutAlso: CPPD
Crystal arthritis caused mainly by calcium pyrophosphate deposition.
Open definition page →Myalgia
Muscle pain.
Open definition page →Myositis
Inflammation of muscle.
Open definition page →Rhabdomyolysis
Rapid breakdown of skeletal muscle releasing muscle-cell contents into the blood. Severe cases can cause kidney injury.
Bone density scanAlso: DEXA · DXA
A low-dose X-ray test that measures bone mineral density, commonly at the hip and spine.
Open definition page →T-score
A bone-density comparison with the average peak bone density of a young healthy adult.
Open definition page →Z-score
A bone-density comparison with people of the same age and sex.
Open definition page →Fragility fracture
A fracture caused by a level of trauma that would not normally break healthy bone, often indicating osteoporosis.
Open definition page →Skin & Dermatology
Inflammatory, infectious, pigmented and malignant skin terms.
Dermatitis
Inflammation of the skin, commonly causing redness, itching and irritation.
Open definition page →Eczema
A group of inflammatory skin conditions causing itch, dryness and rash.
Open definition page →Psoriasis
A chronic immune-mediated skin disease causing well-defined scaly plaques and sometimes joint inflammation.
Open definition page →Cellulitis
A bacterial infection of deeper skin and subcutaneous tissue causing redness, warmth, swelling and tenderness.
Open definition page →Abscess
A collection of pus within tissue caused by infection.
Open definition page →BoilAlso: Furuncle
A painful pus-filled infection of a hair follicle and surrounding tissue.
Open definition page →MoleAlso: Naevus · Nevus
A usually benign collection of pigment-producing cells in the skin.
Open definition page →Melanoma
A malignant tumour of melanocytes, the pigment-producing cells of skin and other tissues.
Open definition page →Basal cell carcinomaAlso: BCC
A common skin cancer arising from basal cells. It usually grows locally and rarely metastasises.
Open definition page →Squamous cell carcinoma of skin
A skin cancer arising from squamous cells that can invade and, in some cases, spread.
Open definition page →Actinic keratosisAlso: Solar keratosis
A rough sun-damaged skin lesion that can sometimes progress to squamous cell carcinoma.
Open definition page →Hidradenitis suppurativaAlso: HS
A chronic inflammatory skin disease causing painful nodules, abscesses and tunnels, mainly in skin folds.
Open definition page →Alopecia
Hair loss from the scalp or body.
Open definition page →Alopecia areata
An autoimmune condition causing well-defined patches of hair loss.
Open definition page →Ulceration
Loss of the surface layer of skin or mucosa creating an open sore.
Open definition page →Petechiae
Tiny non-blanching red or purple spots caused by small amounts of bleeding under the skin.
Open definition page →Purpura
Purple or red skin discoloration caused by bleeding into the skin.
Open definition page →Ecchymosis
A larger area of bleeding under the skin, commonly called a bruise.
Open definition page →Pruritus
Itching.
Open definition page →Erythema
Redness of the skin caused by increased blood flow.
Open definition page →Medicines & Pharmacology
Medicine classes, doses, interactions, side effects and common prescribing language.
Prescription medicine
A medicine that legally requires authorisation from an appropriately licensed prescriber.
Open definition page →Over-the-counter medicineAlso: OTC
A medicine available without an individual prescription when used according to authorised conditions.
Open definition page →Generic name
The standard non-brand name of a medicine based on its active ingredient.
Open definition page →Brand name
The commercial name under which a medicine is marketed.
Open definition page →Active ingredient
The substance in a medicine responsible for its therapeutic effect.
Open definition page →Dose
The amount of medicine taken or administered at one time.
Open definition page →Dosage regimen
The planned amount, timing, route and frequency of a medicine.
Open definition page →Half-life
The time required for the amount of a medicine in the body or blood to fall by approximately half.
Open definition page →Bioavailability
The proportion of a medicine dose that reaches systemic circulation in active form.
Open definition page →Contraindicated
Describes a treatment that should not be used in a particular situation because risk outweighs expected benefit.
Open definition page →Drug interaction
A change in a medicine's effect caused by another medicine, food, supplement, alcohol or substance.
Open definition page →Side effect
An unwanted effect occurring at normal therapeutic doses.
Open definition page →Adverse drug reactionAlso: ADR
A harmful or unintended response to a medicine used at normal doses.
Open definition page →Allergic drug reaction
An immune-mediated reaction to a medicine, ranging from rash to anaphylaxis.
Open definition page →Antibiotic
A medicine used to treat susceptible bacterial infections.
Open definition page →Antiviral
A medicine that inhibits replication or effects of a virus.
Open definition page →Antifungal
A medicine used to treat fungal infection.
Open definition page →Antiparasitic
A medicine used to treat infections caused by parasites.
Open definition page →AnalgesicAlso: Painkiller
A medicine used to reduce pain.
Open definition page →ParacetamolAlso: Acetaminophen
A common analgesic and fever-reducing medicine. Excessive doses can cause serious liver injury.
Open definition page →NSAIDAlso: Non-steroidal anti-inflammatory drug
A non-steroidal anti-inflammatory drug used for pain and inflammation, such as ibuprofen or naproxen.
Open definition page →CorticosteroidAlso: Steroid
A medicine related to adrenal steroid hormones that strongly reduces inflammation and immune activity.
Open definition page →Prednisolone
An oral corticosteroid used to treat many inflammatory and immune conditions.
Open definition page →Antihistamine
A medicine blocking histamine effects, commonly used for allergies and itching.
Open definition page →AnticoagulantAlso: Blood thinner
A medicine that reduces the blood's ability to form clots. It does not literally thin the blood.
Open definition page →Antiplatelet
A medicine that reduces platelet activation and clot formation, such as aspirin or clopidogrel.
Open definition page →Warfarin
An oral anticoagulant monitored using INR.
Open definition page →DOACAlso: Direct oral anticoagulant
A direct oral anticoagulant such as apixaban, rivaroxaban, edoxaban or dabigatran.
Open definition page →Statin
A medicine that lowers LDL cholesterol and reduces cardiovascular risk in appropriate patients.
Open definition page →ACE inhibitorAlso: ACEi
A medicine used in hypertension, heart failure and kidney protection by blocking angiotensin-converting enzyme.
Open definition page →ARBAlso: Angiotensin receptor blocker
A medicine blocking the angiotensin II receptor, used in hypertension and selected heart and kidney conditions.
Open definition page →Beta blocker
A medicine that blocks beta-adrenergic receptors, slowing heart rate and reducing cardiac workload.
Open definition page →Calcium-channel blockerAlso: CCB
A class used for hypertension, angina and some heart-rhythm conditions.
Open definition page →DiureticAlso: Water tablet
A medicine that increases kidney excretion of sodium and water.
Open definition page →Proton-pump inhibitorAlso: PPI
A medicine that strongly reduces stomach-acid production.
Open definition page →Metformin
A common type 2 diabetes medicine that reduces liver glucose production and improves insulin sensitivity.
Open definition page →GLP-1 receptor agonistAlso: GLP-1 RA
A medicine that mimics GLP-1 signalling to improve glucose regulation, reduce appetite and slow gastric emptying.
Open definition page →SGLT2 inhibitorAlso: SGLT2i
A medicine that increases urinary glucose excretion and can provide heart and kidney benefits in selected patients.
Open definition page →Insulin analogue
A modified form of insulin designed to have a particular onset and duration of action.
Open definition page →SSRIAlso: Selective serotonin reuptake inhibitor
A common antidepressant class that increases serotonin signalling by blocking serotonin reuptake.
Open definition page →SNRIAlso: Serotonin-noradrenaline reuptake inhibitor
An antidepressant class inhibiting serotonin and noradrenaline reuptake.
Open definition page →AnticonvulsantAlso: Antiseizure medication
A medicine used to prevent seizures; some are also used for pain or mood disorders.
Open definition page →Opioid analgesic
A pain medicine acting on opioid receptors. It can cause sedation, constipation, dependence and respiratory suppression.
Open definition page →Antiemetic
A medicine used to prevent or treat nausea and vomiting.
Open definition page →Laxative
A medicine used to treat constipation by changing stool consistency, bowel movement or both.
Open definition page →Biologic
A medicine made using living systems, often a protein or antibody designed to act on a specific biological target.
Open definition page →Biosimilar
A biological medicine shown to be highly similar to an authorised reference biologic without clinically meaningful differences.
Open definition page →Taper
A planned gradual reduction in medicine dose rather than stopping suddenly.
Open definition page →Discontinuation syndrome
Symptoms that can occur when certain medicines, especially some antidepressants, are stopped abruptly or reduced too quickly.
Open definition page →Therapeutic drug monitoringAlso: TDM
Measuring blood concentrations of selected medicines to help keep exposure within a useful and safe range.
Open definition page →Polypharmacy
Use of multiple medicines at the same time, especially when the number or complexity increases risk.
Open definition page →General Clinical Terms & Symptoms
Words frequently found in reports, consultations and discharge letters.
Acute
Beginning suddenly or lasting a relatively short period. Acute does not necessarily mean severe.
Open definition page →Chronic
Persisting for a long period, often months or years.
Open definition page →Subacute
Developing or lasting over an intermediate period between acute and chronic.
Open definition page →Idiopathic
A condition for which no specific cause has been identified.
Open definition page →Iatrogenic
Caused unintentionally by medical treatment or a healthcare intervention.
Open definition page →Congenital
Present from birth, whether caused by genetics, development or another prenatal factor.
Open definition page →Acquired
Developed after birth rather than present from birth.
Open definition page →Hereditary
Passed through genetic inheritance from parent to child.
Open definition page →Risk factor
A characteristic or exposure associated with a higher probability of developing a disease.
Open definition page →Prognosis
The expected course or likely outcome of a disease.
Open definition page →Diagnosis
Identification of a disease or condition based on symptoms, examination and tests.
Open definition page →Differential diagnosis
The list of possible conditions that could explain a patient's symptoms or findings.
Open definition page →Screening
Testing people without symptoms to identify disease or increased risk earlier.
Open definition page →Sensitivity
In diagnostic testing, the ability of a test to correctly identify people who truly have the condition.
Open definition page →Specificity
In diagnostic testing, the ability of a test to correctly identify people who do not have the condition.
Open definition page →False positive
A test result suggesting disease when the disease is actually absent.
Open definition page →False negative
A test result suggesting disease is absent when it is actually present.
Open definition page →Positive predictive valueAlso: PPV
The probability that a person with a positive test result truly has the condition.
Open definition page →Negative predictive valueAlso: NPV
The probability that a person with a negative test result truly does not have the condition.
Open definition page →Symptom
A problem experienced and reported by the patient, such as pain or nausea.
Open definition page →Sign
An objective finding observed or measured by a clinician, such as fever, rash or high blood pressure.
Open definition page →Fever
A body temperature above the normal range, commonly related to infection or inflammation.
Open definition page →Pyrexia
Another medical term for fever.
Open definition page →Fatigue
A persistent sense of tiredness, low energy or reduced physical or mental capacity.
Open definition page →Malaise
A general feeling of being unwell or lacking normal well-being.
Open definition page →Pain
An unpleasant sensory and emotional experience associated with actual or potential tissue injury.
Open definition page →Acute pain
Pain developing over a short period, often related to injury, inflammation or surgery.
Open definition page →Chronic pain
Pain that persists or recurs for longer than expected for normal healing.
Open definition page →OedemaAlso: Edema
Swelling caused by excess fluid in body tissues.
Open definition page →Inflammation
The body's response to injury, infection or immune activation. Inflammation is not the same as infection.
Open definition page →Dehydration
A deficit of body water, with or without loss of electrolytes.
Open definition page →Nausea
The unpleasant sensation of feeling that vomiting may occur.
Open definition page →VomitingAlso: Emesis
Forceful expulsion of stomach contents through the mouth.
Open definition page →Anorexia
Loss of appetite. In clinical notes this term can mean reduced appetite and does not automatically mean anorexia nervosa.
Open definition page →Cachexia
Complex loss of weight, muscle and strength associated with chronic disease.
Open definition page →Cyanosis
Bluish or grey discoloration of skin or mucous membranes caused by abnormal oxygenation or circulation.
Open definition page →Clubbing
Bulbous enlargement of the ends of fingers or toes, associated with several chronic conditions.
Open definition page →Lymphadenopathy
Abnormal enlargement or change in lymph nodes.
Open definition page →Organomegaly
Abnormal enlargement of an internal organ.
Open definition page →TachypnoeaAlso: Tachypnea
Breathing faster than expected.
Open definition page →Atrophy
Shrinkage or wasting of a tissue or organ.
Open definition page →Hypertrophy
Increase in cell size causing enlargement of a tissue or organ.
Open definition page →Hyperplasia
Increase in the number of cells within a tissue.
Open definition page →Necrosis
Uncontrolled death of cells or tissue due to injury, loss of blood supply, toxins or severe inflammation.
Open definition page →IschaemiaAlso: Ischemia
Insufficient blood supply to a tissue, reducing oxygen and nutrient delivery.
Open definition page →Infarction
Death of tissue caused by prolonged loss of blood supply.
Open definition page →Bilateral
Present on both sides of the body.
Open definition page →Unilateral
Present on one side only.
Open definition page →Proximal
Closer to the centre of the body or point of origin.
Open definition page →Distal
Farther from the centre of the body or point of origin.
Open definition page →Anterior
Toward the front of the body.
Open definition page →Posterior
Toward the back of the body.
Open definition page →Medial
Toward the midline of the body.
Open definition page →Lateral
Away from the midline of the body.
Open definition page →Medical Word Building
Prefixes, roots and suffixes that help decode unfamiliar medical words.
cardio-
A common medical word part meaning “heart”. It can help decode unfamiliar terminology.
neuro-
A common medical word part meaning “nervous system or nerves”. It can help decode unfamiliar terminology.
hepato-
A common medical word part meaning “liver”. It can help decode unfamiliar terminology.
nephro-
A common medical word part meaning “kidney”. It can help decode unfamiliar terminology.
gastro-
A common medical word part meaning “stomach”. It can help decode unfamiliar terminology.
entero-
A common medical word part meaning “intestine”. It can help decode unfamiliar terminology.
colo-
A common medical word part meaning “colon”. It can help decode unfamiliar terminology.
dermato-
A common medical word part meaning “skin”. It can help decode unfamiliar terminology.
osteo-
A common medical word part meaning “bone”. It can help decode unfamiliar terminology.
arthro-
A common medical word part meaning “joint”. It can help decode unfamiliar terminology.
myo-
A common medical word part meaning “muscle”. It can help decode unfamiliar terminology.
haemato-
A common medical word part meaning “blood”. It can help decode unfamiliar terminology.
onco-
A common medical word part meaning “tumour or cancer”. It can help decode unfamiliar terminology.
pneumo-
A common medical word part meaning “lung or air”. It can help decode unfamiliar terminology.
thyro-
A common medical word part meaning “thyroid”. It can help decode unfamiliar terminology.
glyco-
A common medical word part meaning “sugar or glucose”. It can help decode unfamiliar terminology.
angio-
A common medical word part meaning “blood vessel”. It can help decode unfamiliar terminology.
uro-
A common medical word part meaning “urinary tract”. It can help decode unfamiliar terminology.
gynae-
A common medical word part meaning “female reproductive system”. It can help decode unfamiliar terminology.
hystero-
A common medical word part meaning “uterus”. It can help decode unfamiliar terminology.
cephalo-
A common medical word part meaning “head”. It can help decode unfamiliar terminology.
encephalo-
A common medical word part meaning “brain”. It can help decode unfamiliar terminology.
rhino-
A common medical word part meaning “nose”. It can help decode unfamiliar terminology.
oto-
A common medical word part meaning “ear”. It can help decode unfamiliar terminology.
ophthalmo-
A common medical word part meaning “eye”. It can help decode unfamiliar terminology.
-itis
A common medical word part meaning “inflammation”. It can help decode unfamiliar terminology.
-osis
A common medical word part meaning “a condition or process”. It can help decode unfamiliar terminology.
-oma
A common medical word part meaning “a tumour or mass”. It can help decode unfamiliar terminology.
-algia
A common medical word part meaning “pain”. It can help decode unfamiliar terminology.
-pathy
A common medical word part meaning “disease or disorder”. It can help decode unfamiliar terminology.
-megaly
A common medical word part meaning “enlargement”. It can help decode unfamiliar terminology.
-penia
A common medical word part meaning “too few or a reduced amount”. It can help decode unfamiliar terminology.
-cytosis
A common medical word part meaning “an increased number of cells”. It can help decode unfamiliar terminology.
-ectomy
A common medical word part meaning “surgical removal”. It can help decode unfamiliar terminology.
-otomy
A common medical word part meaning “cutting into or creating an incision”. It can help decode unfamiliar terminology.
-ostomy
A common medical word part meaning “surgically creating an opening”. It can help decode unfamiliar terminology.
-scopy
A common medical word part meaning “visual examination using a scope”. It can help decode unfamiliar terminology.
-gram
A common medical word part meaning “a record or image”. It can help decode unfamiliar terminology.
-graphy
A common medical word part meaning “the process of recording or imaging”. It can help decode unfamiliar terminology.
-emia
A common medical word part meaning “a condition involving the blood”. It can help decode unfamiliar terminology.
hyper-
A common medical word part meaning “above normal or excessive”. It can help decode unfamiliar terminology.
hypo-
A common medical word part meaning “below normal or reduced”. It can help decode unfamiliar terminology.
tachy-
A common medical word part meaning “fast”. It can help decode unfamiliar terminology.
brady-
A common medical word part meaning “slow”. It can help decode unfamiliar terminology.
dys-
A common medical word part meaning “abnormal, difficult or painful”. It can help decode unfamiliar terminology.
a- / an-
A common medical word part meaning “without or absence of”. It can help decode unfamiliar terminology.
peri-
A common medical word part meaning “around”. It can help decode unfamiliar terminology.
endo-
A common medical word part meaning “inside or within”. It can help decode unfamiliar terminology.
epi-
A common medical word part meaning “on, upon or above”. It can help decode unfamiliar terminology.
sub-
A common medical word part meaning “under or below”. It can help decode unfamiliar terminology.
intra-
A common medical word part meaning “within”. It can help decode unfamiliar terminology.
inter-
A common medical word part meaning “between”. It can help decode unfamiliar terminology.
trans-
A common medical word part meaning “across or through”. It can help decode unfamiliar terminology.
poly-
A common medical word part meaning “many”. It can help decode unfamiliar terminology.
oligo-
A common medical word part meaning “few or reduced”. It can help decode unfamiliar terminology.
micro-
A common medical word part meaning “small”. It can help decode unfamiliar terminology.
macro-
A common medical word part meaning “large”. It can help decode unfamiliar terminology.
neo-
A common medical word part meaning “new”. It can help decode unfamiliar terminology.
Common Abbreviations
Frequently seen shorthand in results, notes and prescriptions.
BP
Blood pressure.
Open definition page →HR
Heart rate.
Open definition page →RR
Respiratory rate, meaning breaths per minute.
Open definition page →Temp
Body temperature.
Open definition page →SpO2
Peripheral oxygen saturation estimated by pulse oximetry.
Open definition page →PRN
A medicine or treatment to be used when needed rather than on a fixed schedule.
Open definition page →NPO
Nothing by mouth; no food or drink for a specified period.
Open definition page →NBM
Nil by mouth.
Open definition page →Hx
History.
Open definition page →PMH
Past medical history.
Open definition page →FH
Family history.
Open definition page →SH
Social history.
Open definition page →Dx
Diagnosis.
Open definition page →Tx
Treatment.
Open definition page →Rx
Prescription or treatment, depending on context.
Open definition page →Bx
Biopsy.
Open definition page →US
Ultrasound.
Open definition page →CXR
Chest X-ray.
Open definition page →CT
Computed tomography.
Open definition page →FBC
Full blood count.
Open definition page →LFT
Liver function tests.
Open definition page →U&E
Urea and electrolytes, a common kidney/electrolyte blood-test panel.
Open definition page →Hb
Haemoglobin.
Open definition page →WBC
White blood cell count.
Open definition page →RBC
Red blood cell count.
Open definition page →PLT
Platelet count.
Open definition page →ANC
Absolute neutrophil count.
Open definition page →GCS
Glasgow Coma Scale, a structured measure of consciousness.
Open definition page →BMI
Body mass index.
Open definition page →SC
Subcutaneous.
Open definition page →PO
By mouth, from the Latin per os.
Open definition page →SOB
Shortness of breath in many medical notes; context matters because abbreviations can be ambiguous.
Open definition page →NAD
No abnormality detected in many clinical notes, though abbreviation usage varies.
Open definition page →WNL
Within normal limits.
Open definition page →NKDA
No known drug allergies.
Open definition page →Try a shorter word, a common abbreviation or the everyday name of the condition.
Accurate enough to be useful. Simple enough to understand.
The dictionary preserves clinically important distinctions while avoiding unnecessary jargon.
Plain English first
Definitions start with what the word means, not with Latin, histology or molecular terminology.
Context matters
An abnormal result, lesion or imaging term is not interpreted as a diagnosis in isolation.
Trusted reference framework
Terminology is cross-checked against patient-facing resources from MedlinePlus/NLM, NCI and CDC.
