Healthway Medical Dictionary

Medical language, translated into normal language.

Search the words you see in blood results, ultrasound reports, prescriptions, hospital letters and medical news. Definitions are written for patients and the public—not for an exam textbook.

768 terms & abbreviations19 categoriesEveryday aliases includedReviewed 15 Aug 2026
A useful rule: words such as lesion, nodule, mass, positive or abnormal do not automatically mean cancer or serious disease. Medical language always needs context.

Blood & Laboratory

FBC/CBC, iron studies, clotting, inflammatory markers and common laboratory terminology.

62 terms
Full blood countAlso: FBC · CBC · Complete blood count

A blood test that counts red cells, white cells and platelets and reports measurements such as haemoglobin and red-cell size.

Open definition page →
HaemoglobinAlso: Hemoglobin · Hb

The oxygen-carrying protein inside red blood cells. Low haemoglobin is a key feature of anaemia.

Open definition page →
HaematocritAlso: Hematocrit · Hct · PCV

The proportion of blood volume made up of red blood cells.

Open definition page →
Red blood cell countAlso: RBC

The number of red blood cells in a measured volume of blood.

Open definition page →
White blood cell countAlso: WBC

The total number of infection- and immunity-related white blood cells.

Open definition page →
Platelet countAlso: PLT

The number of platelets in blood. Platelets are essential for normal clot formation.

Open definition page →
MCVAlso: Mean corpuscular volume

The average size of red blood cells. A low MCV suggests microcytosis; a high MCV suggests macrocytosis.

Open definition page →
MCHAlso: Mean corpuscular haemoglobin

The average amount of haemoglobin in each red blood cell.

Open definition page →
MCHCAlso: Mean corpuscular haemoglobin concentration

The average concentration of haemoglobin inside red blood cells.

Open definition page →
RDWAlso: Red cell distribution width

A measure of how much red blood cells vary in size.

Open definition page →
Neutrophils

White blood cells especially important in bacterial infection and acute inflammation.

Open definition page →
Absolute neutrophil countAlso: ANC

The actual number of neutrophils in blood, rather than their percentage.

Open definition page →
Neutropenia

A lower-than-normal neutrophil count. Infection risk rises when neutropenia becomes more severe.

Useful context: Fever with significant neutropenia can require urgent assessment.
Open definition page →
Neutrophilia

A higher-than-normal neutrophil count, commonly seen with infection, inflammation, stress or corticosteroid treatment.

Open definition page →
Lymphocytes

White blood cells central to adaptive immunity, including antiviral responses and antibody production.

Open definition page →
Lymphocytosis

A higher-than-normal lymphocyte count, seen with some infections and blood disorders.

Open definition page →
Lymphopenia

A lower-than-normal lymphocyte count, which can occur with acute illness, medicines and immune disorders.

Open definition page →
Monocytes

White blood cells involved in longer-term immune responses and clearance of damaged material.

Open definition page →
Eosinophils

White blood cells that can increase in allergies, asthma, parasitic infection and some drug reactions.

Open definition page →
Basophils

A small group of white blood cells involved in allergic and inflammatory signalling.

Open definition page →
Immature granulocytesAlso: IG

Young white blood cells released from bone marrow, often increased during strong marrow responses.

Open definition page →
Left shift

A laboratory description meaning increased immature neutrophil forms are present, often during acute infection or inflammation.

Open definition page →
Blood filmAlso: Peripheral smear

A blood sample spread thinly on a slide so the shape and appearance of cells can be examined under a microscope.

Open definition page →
AnaemiaAlso: Anemia

A condition in which haemoglobin is too low to carry oxygen normally. Causes include iron deficiency, bleeding and chronic disease.

Open definition page →
Microcytosis

Red blood cells that are smaller than usual, usually reflected by a low MCV.

Open definition page →
Macrocytosis

Red blood cells that are larger than usual, usually reflected by a high MCV.

Open definition page →
Hypochromia

Red blood cells containing less haemoglobin than usual, often seen with iron deficiency.

Open definition page →
Anisocytosis

More variation in red-cell size than usual, often associated with a raised RDW.

Open definition page →
Poikilocytosis

More variation in red-cell shape than usual.

Open definition page →
Reticulocyte count

A count of young red blood cells that helps show how actively bone marrow is making new red cells.

Open definition page →
Ferritin

A protein that stores iron. Low ferritin usually indicates depleted iron stores; ferritin can rise during inflammation.

Open definition page →
Serum iron

The amount of circulating iron measured at one point in time. It varies and is usually interpreted with other iron studies.

Open definition page →
Transferrin

A protein that transports iron in the blood.

Open definition page →
Transferrin saturationAlso: TSAT

The percentage of transferrin carrying iron. It helps assess iron deficiency and iron overload.

Open definition page →
TIBCAlso: Total iron-binding capacity

An estimate of how much iron the blood could carry if transferrin were fully occupied.

Open definition page →
Iron deficiency

A state in which the body has insufficient iron. It can exist before haemoglobin falls enough to cause anaemia.

Open definition page →
Iron-deficiency anaemia

Anaemia caused by insufficient iron for normal haemoglobin production.

Open definition page →
Vitamin B12

A vitamin needed for normal blood formation and neurological function.

Open definition page →
FolateAlso: Folic acid

A B vitamin required for DNA synthesis and normal blood-cell production.

Open definition page →
ESRAlso: Erythrocyte sedimentation rate

A non-specific marker that can increase with inflammation, infection, autoimmune disease and other conditions.

Open definition page →
CRPAlso: C-reactive protein

A liver-produced protein that rises with inflammation or infection. It is useful for trends but does not identify the cause by itself.

Open definition page →
Procalcitonin

A blood marker that can rise in significant bacterial infection and sepsis, but must be interpreted clinically.

Open definition page →
Blood culture

A laboratory test that looks for bacteria or fungi circulating in the bloodstream.

Open definition page →
Coagulation screenAlso: Clotting screen

A group of tests used to assess parts of the blood-clotting system.

Open definition page →
PTAlso: Prothrombin time

A clotting test used to assess part of the coagulation pathway and to calculate INR.

Open definition page →
INRAlso: International normalised ratio

A standardised clotting measurement commonly used to monitor warfarin.

Open definition page →
aPTTAlso: Activated partial thromboplastin time

A clotting test used to assess another part of the coagulation system and sometimes to monitor unfractionated heparin.

Open definition page →
Fibrinogen

A blood protein converted into fibrin when a clot forms.

Open definition page →
D-dimer

A fragment produced when a clot is broken down. An elevated result is non-specific and does not by itself prove thrombosis.

Open definition page →
Blood group

Classification of blood based on red-cell antigens, most commonly the ABO and Rh systems.

Open definition page →
Crossmatch

A compatibility test performed before selected blood transfusions.

Open definition page →
HaemolysisAlso: Hemolysis

Breakdown of red blood cells. It can happen in the body or accidentally after a blood sample is collected.

Open definition page →
LDHAlso: Lactate dehydrogenase

An enzyme found in many tissues that can rise when cells are damaged.

Open definition page →
Haptoglobin

A protein that binds free haemoglobin. Low levels can support certain diagnoses of haemolysis.

Open definition page →
Direct antiglobulin testAlso: DAT · Direct Coombs test

A test that checks whether antibodies or complement are attached to red blood cells.

Open definition page →
Reference range

The interval in which most results from a defined reference population fall. A result just outside the range does not automatically mean disease.

Open definition page →
Critical result

A laboratory value considered dangerous enough that rapid clinical attention may be required.

Open definition page →
Specimen

The sample sent for testing, such as blood, urine, stool, swab or tissue.

Open definition page →
Haemolysed sampleAlso: Hemolyzed sample

A blood sample in which red cells broke down after collection, potentially making some results unreliable.

Open definition page →
Clotted sample

A blood sample that formed a clot when the requested test required unclotted blood.

Open definition page →
Phlebotomy

The practice of drawing blood from a vein for testing or treatment.

Open definition page →
VenepunctureAlso: Venipuncture

Insertion of a needle into a vein, most commonly to collect blood.

Open definition page →

Kidney, Liver & Biochemistry

Kidney function, electrolytes, liver enzymes, acid–base balance and metabolism.

45 terms
Creatinine

A waste product generated mainly from muscle metabolism. It is used to estimate kidney filtration.

Open definition page →
eGFRAlso: Estimated glomerular filtration rate

An estimate of how well the kidneys filter blood, calculated from creatinine and patient characteristics.

Open definition page →
Urea

A waste product formed from protein metabolism and cleared mainly by the kidneys.

Open definition page →
Acute kidney injuryAlso: AKI

A sudden deterioration in kidney function occurring over hours to days.

Open definition page →
Chronic kidney diseaseAlso: CKD

Long-term abnormal kidney structure or function.

Open definition page →
Proteinuria

Excess protein in urine. Persistent proteinuria can be a marker of kidney disease.

Open definition page →
Albuminuria

Albumin in urine above the expected level, an important marker of kidney and cardiovascular risk.

Open definition page →
ACRAlso: Albumin-to-creatinine ratio

A urine test comparing albumin with creatinine to estimate albumin loss.

Open definition page →
Electrolytes

Minerals in body fluids that carry electrical charge, including sodium, potassium, chloride and bicarbonate.

Open definition page →
Sodium

A major blood electrolyte involved in fluid balance, nerve function and blood pressure.

Open definition page →
HyponatraemiaAlso: Hyponatremia

A lower-than-normal sodium concentration. Symptoms depend on how low it is and how quickly it developed.

Open definition page →
HypernatraemiaAlso: Hypernatremia

A higher-than-normal sodium concentration, often reflecting a relative shortage of body water.

Open definition page →
Potassium

An electrolyte essential for normal nerve, muscle and heart electrical activity.

Open definition page →
HypokalaemiaAlso: Hypokalemia

A low blood potassium level that can cause weakness and, when significant, heart-rhythm problems.

Open definition page →
HyperkalaemiaAlso: Hyperkalemia

A high blood potassium level that can disturb cardiac electrical activity.

Useful context: Marked hyperkalaemia can be a medical emergency.
⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Calcium

A mineral important for bone, muscle contraction, nerve transmission and many cellular processes.

Open definition page →
Corrected calcium

An estimate of calcium adjusted for albumin when total calcium is measured.

Open definition page →
Ionised calciumAlso: Ionized calcium

The biologically active form of calcium circulating freely in blood.

Open definition page →
Magnesium

An electrolyte involved in muscle, nerve and cardiac function.

Open definition page →
Phosphate

A mineral involved in bone, energy metabolism and cell function.

Open definition page →
Bicarbonate

A major blood buffer that helps maintain acid–base balance.

Open definition page →
Anion gap

A calculated value from electrolytes that can help classify some disturbances of blood acidity.

Open definition page →
Liver function testsAlso: LFTs

A group of tests used to assess liver-cell injury, bile flow and protein production.

Open definition page →
ALTAlso: Alanine aminotransferase

A liver-enriched enzyme that often rises with liver-cell injury.

Open definition page →
ASTAlso: Aspartate aminotransferase

An enzyme found in liver, muscle and other tissues that can rise with liver or muscle injury.

Open definition page →
ALPAlso: Alkaline phosphatase

An enzyme found particularly in bile ducts and bone.

Open definition page →
GGTAlso: Gamma-glutamyl transferase

An enzyme often used to help identify a liver or bile-duct source of abnormal liver tests.

Open definition page →
Bilirubin

A yellow pigment produced when haemoglobin is broken down. High levels can cause jaundice.

Open definition page →
Albumin

The main protein in blood plasma, important for fluid balance and transport of many substances.

Open definition page →
Total protein

A measurement of major blood proteins, particularly albumin and globulins.

Open definition page →
JaundiceAlso: Icterus

Yellowing of the skin or eyes caused by increased bilirubin.

Open definition page →
Cholestasis

Reduced or obstructed flow of bile from the liver.

Open definition page →
Hepatitis

Inflammation of the liver caused by infection, alcohol, medicines, autoimmune disease or other conditions.

Open definition page →
SteatosisAlso: Fatty liver

Excess fat accumulation in cells, most commonly used to describe fatty liver.

Open definition page →
MASLDAlso: Metabolic dysfunction-associated steatotic liver disease

The current term for fatty liver disease associated with metabolic dysfunction.

Open definition page →
MASHAlso: Metabolic dysfunction-associated steatohepatitis

Metabolic fatty liver disease with liver-cell injury and inflammation.

Open definition page →
Fibrosis

Formation of excess scar tissue after ongoing or repeated tissue injury.

Open definition page →
Cirrhosis

Advanced scarring of the liver that distorts normal structure and can impair function.

Open definition page →
Amylase

A digestive enzyme that can rise in pancreatic and some other conditions.

Open definition page →
Lipase

A digestive enzyme commonly measured when pancreatitis is suspected.

Open definition page →
Lactate

A substance produced during metabolism that can rise with poor tissue perfusion, severe infection, seizures and other states.

Open definition page →
Acidosis

A process that makes body fluids more acidic than normal.

Open definition page →
Alkalosis

A process that makes body fluids more alkaline than normal.

Open definition page →
Blood gasAlso: ABG · VBG

A test measuring oxygen, carbon dioxide and acid–base status, usually from arterial or venous blood.

Open definition page →
Osmolality

A measure of the concentration of dissolved particles in a fluid such as blood or urine.

Open definition page →

Heart & Circulation

Blood pressure, rhythm, coronary disease, heart failure and vascular terminology.

46 terms
Blood pressure

The force exerted by circulating blood against artery walls, expressed as systolic over diastolic pressure.

Open definition page →
Systolic blood pressure

The upper blood-pressure number, representing arterial pressure when the heart contracts.

Open definition page →
Diastolic blood pressure

The lower blood-pressure number, representing arterial pressure when the heart relaxes between beats.

Open definition page →
HypertensionAlso: High blood pressure

Persistently elevated blood pressure. It often causes no symptoms but increases long-term cardiovascular and kidney risk.

Open definition page →
HypotensionAlso: Low blood pressure

Blood pressure that is lower than expected. It matters mainly when it causes symptoms or reflects illness.

Open definition page →
Heart rateAlso: Pulse

The number of heart beats per minute.

Open definition page →
Tachycardia

A heart rate faster than expected for the situation.

Open definition page →
Bradycardia

A heart rate slower than expected for the situation.

Open definition page →
Palpitations

The sensation of being aware of the heartbeat, such as racing, pounding, fluttering or skipped beats.

Open definition page →
Arrhythmia

An abnormal heart rhythm that may be too fast, too slow or irregular.

Open definition page →
Atrial fibrillationAlso: AF · AFib

A common irregular rhythm arising in the upper chambers of the heart. It can increase stroke risk.

Open definition page →
Atrial flutter

A rapid organised rhythm arising in the atria, related to but different from atrial fibrillation.

Open definition page →
Ectopic beatAlso: Premature beat

An extra heartbeat occurring earlier than the next expected normal beat.

Open definition page →
PVCAlso: Premature ventricular contraction · Ventricular ectopic

An extra heartbeat arising from the ventricles.

Open definition page →
PACAlso: Premature atrial contraction

An extra heartbeat arising from the atria.

Open definition page →
SVTAlso: Supraventricular tachycardia

A rapid heart rhythm that starts above the ventricles.

Open definition page →
Ventricular tachycardiaAlso: VT

A rapid rhythm originating in the ventricles. Sustained VT can be life-threatening.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Ventricular fibrillationAlso: VF

Chaotic ventricular electrical activity that stops effective blood circulation.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Angina

Chest discomfort caused by temporary insufficient blood flow to heart muscle, usually from coronary artery disease.

Open definition page →
Myocardial infarctionAlso: Heart attack · MI

Death of heart-muscle tissue caused by prolonged interruption of blood supply, most often from a blocked coronary artery.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Acute coronary syndromeAlso: ACS

Urgent conditions caused by suddenly reduced blood flow to the heart, including some heart attacks and unstable angina.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Coronary artery diseaseAlso: CAD

Narrowing or blockage of the arteries supplying the heart, usually due to atherosclerosis.

Open definition page →
Atherosclerosis

Build-up of cholesterol-rich plaque in artery walls.

Open definition page →
Heart failure

A syndrome in which the heart cannot pump or fill well enough to meet the body's needs without abnormal pressures.

Open definition page →
Ejection fractionAlso: EF

The percentage of blood pumped out of a ventricle with each contraction, usually referring to the left ventricle.

Open definition page →
Cardiomyopathy

Disease of heart muscle affecting its size, thickness, stiffness or pumping ability.

Open definition page →
Myocarditis

Inflammation of heart muscle.

Open definition page →
Pericarditis

Inflammation of the sac surrounding the heart.

Open definition page →
Endocarditis

Infection or inflammation of the inner lining of the heart, often affecting valves.

Open definition page →
Heart murmur

A sound made by turbulent blood flow through the heart. Some murmurs are harmless; others reflect valve or structural disease.

Open definition page →
Valve stenosis

Narrowing of a heart valve that obstructs forward blood flow.

Open definition page →
Valve regurgitation

Leakage backward through a heart valve that does not close completely.

Open definition page →
Aortic stenosis

Narrowing of the aortic valve between the left ventricle and the aorta.

Open definition page →
Mitral regurgitation

Leakage through the mitral valve from the left ventricle back into the left atrium.

Open definition page →
Deep vein thrombosisAlso: DVT

A blood clot in a deep vein, most commonly in the leg.

Open definition page →
Pulmonary embolismAlso: PE

A blockage in a lung artery, usually caused by a clot that travelled from a deep vein.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Peripheral arterial diseaseAlso: PAD

Reduced blood flow to the limbs because arteries have narrowed, usually from atherosclerosis.

Open definition page →
Aneurysm

Abnormal widening or ballooning of a blood-vessel wall.

Open definition page →
ECGAlso: Electrocardiogram · EKG

A recording of the heart's electrical activity using electrodes on the skin.

Open definition page →
Holter monitor

A portable ECG recorder worn for hours or days to detect intermittent rhythm abnormalities.

Open definition page →
Ambulatory blood pressure monitoringAlso: ABPM

A portable device that measures blood pressure repeatedly over 24 hours or longer.

Open definition page →
Echocardiogram

An ultrasound examination of the heart assessing structure, valve function and pumping.

Open definition page →
Cardioversion

A procedure that restores a normal heart rhythm using an electrical shock or medication.

Open definition page →
Pacemaker

An implanted device that delivers electrical impulses when the heart rhythm is too slow or unreliable.

Open definition page →
Stent

A small mesh tube placed inside an artery to keep it open.

Open definition page →
AngioplastyAlso: PCI

A procedure that widens a narrowed artery using a balloon, often followed by a stent.

Open definition page →

Endocrine, Diabetes & Metabolism

Diabetes, thyroid, adrenal hormones, reproductive hormones and metabolic health.

45 terms
Diabetes mellitus

A group of conditions in which blood glucose is persistently too high because insulin is absent, insufficient or not working effectively.

Open definition page →
Type 1 diabetes

An autoimmune form of diabetes in which pancreatic beta cells are destroyed and insulin replacement is required.

Open definition page →
Type 2 diabetes

Diabetes driven mainly by insulin resistance together with progressive failure of insulin production.

Open definition page →
Prediabetes

Blood glucose higher than normal but below the usual diagnostic threshold for diabetes.

Open definition page →
Insulin

A hormone that helps glucose move from blood into cells and regulates metabolism.

Open definition page →
Insulin resistance

A state in which body tissues respond less effectively to insulin.

Open definition page →
HyperglycaemiaAlso: Hyperglycemia

Blood glucose that is higher than normal.

Open definition page →
HypoglycaemiaAlso: Hypoglycemia

Blood glucose that is too low. Severe hypoglycaemia can cause seizures or unconsciousness.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Diabetic ketoacidosisAlso: DKA

A dangerous metabolic emergency caused by severe insulin deficiency, with high ketones and blood acidity.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Hyperosmolar hyperglycaemic stateAlso: HHS

A severe diabetic emergency with extreme hyperglycaemia, dehydration and high blood osmolality.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Ketones

Chemicals produced when the body burns fat for energy. They can become dangerously high in diabetic ketoacidosis.

Open definition page →
C-peptide

A substance released with the body's own insulin and used to estimate endogenous insulin production.

Open definition page →
HbA1cAlso: A1c · Glycated haemoglobin

A blood test estimating average glucose exposure over roughly the previous 2–3 months.

Open definition page →
Fasting glucose

Blood glucose measured after a specified period without food.

Open definition page →
Random glucose

A blood glucose measurement taken without requiring fasting.

Open definition page →
Thyroid gland

A gland in the neck that produces hormones regulating metabolism and many body functions.

Open definition page →
TSHAlso: Thyroid-stimulating hormone

A pituitary hormone that stimulates the thyroid and is commonly the first test used to assess thyroid function.

Open definition page →
Free T4Also: FT4

The unbound circulating form of thyroxine, one of the main thyroid hormones.

Open definition page →
Free T3Also: FT3

The unbound circulating form of triiodothyronine.

Open definition page →
Hypothyroidism

Underactivity of the thyroid gland, causing insufficient thyroid hormone.

Open definition page →
Hyperthyroidism

Excess thyroid hormone production or release.

Open definition page →
Hashimoto thyroiditis

An autoimmune disease that attacks the thyroid and commonly leads to hypothyroidism.

Open definition page →
Graves disease

An autoimmune condition in which antibodies stimulate the thyroid and cause hyperthyroidism.

Open definition page →
Thyroid nodule

A discrete lump within the thyroid gland. Most thyroid nodules are benign.

Open definition page →
GoitreAlso: Goiter

Enlargement of the thyroid gland.

Open definition page →
Cortisol

A steroid hormone produced by the adrenal glands that helps regulate stress response, blood pressure, glucose and inflammation.

Open definition page →
Cushing syndrome

A condition caused by prolonged excessive cortisol exposure.

Open definition page →
Addison disease

Primary adrenal failure causing insufficient cortisol and often aldosterone.

Open definition page →
Adrenal insufficiency

Insufficient production of adrenal steroid hormones, especially cortisol.

Open definition page →
ACTHAlso: Adrenocorticotropic hormone

A pituitary hormone that stimulates the adrenal glands to produce cortisol.

Open definition page →
Testosterone

The main androgen hormone in men and an important hormone in women, influencing sexual function, muscle, bone and red-cell production.

Open definition page →
OestradiolAlso: Estradiol

The main biologically active oestrogen during reproductive years.

Open definition page →
FSHAlso: Follicle-stimulating hormone

A pituitary hormone involved in ovarian follicle development and sperm production.

Open definition page →
LHAlso: Luteinising hormone · Luteinizing hormone

A pituitary hormone involved in ovulation and testosterone production.

Open definition page →
Prolactin

A pituitary hormone best known for stimulating milk production.

Open definition page →
Growth hormoneAlso: GH

A pituitary hormone involved in growth and metabolism.

Open definition page →
IGF-1Also: Insulin-like growth factor 1

A growth factor produced mainly in response to growth hormone.

Open definition page →
Metabolic syndrome

A cluster of central obesity, abnormal glucose, raised blood pressure and abnormal lipids that increases cardiovascular and diabetes risk.

Open definition page →
Body mass indexAlso: BMI

Weight in kilograms divided by height in metres squared. It is a screening measure, not a direct measurement of body fat.

Open definition page →
Obesity

Excess body fat that increases the risk of health problems.

Open definition page →
Visceral fat

Fat stored around internal abdominal organs and strongly associated with metabolic risk.

Open definition page →
Osteoporosis

A condition in which bones become less dense and structurally weaker, increasing fracture risk.

Open definition page →
Osteopenia

Bone mineral density lower than expected but not low enough to meet the standard definition of osteoporosis.

Open definition page →
Vitamin D

A hormone-like vitamin important for calcium balance and bone health.

Open definition page →
Parathyroid hormoneAlso: PTH

A hormone that helps regulate calcium and phosphate levels.

Open definition page →

Digestive System & Liver

Stomach, bowel, gallbladder, pancreas and liver conditions and procedures.

37 terms
Dyspepsia

Upper abdominal discomfort or indigestion, often including fullness, burning, belching or nausea.

Open definition page →
Gastro-oesophageal reflux diseaseAlso: GERD · GORD · Acid reflux

Repeated reflux of stomach contents into the oesophagus causing symptoms or complications.

Open definition page →
OesophagitisAlso: Esophagitis

Inflammation of the oesophagus.

Open definition page →
Gastritis

Inflammation of the stomach lining.

Open definition page →
Peptic ulcer

An open sore in the lining of the stomach or first part of the small intestine.

Open definition page →
Helicobacter pyloriAlso: H. pylori

A bacterium associated with gastritis, ulcers and increased gastric-cancer risk.

Open definition page →
Dysphagia

Difficulty swallowing.

Open definition page →
Odynophagia

Pain when swallowing.

Open definition page →
HaematemesisAlso: Hematemesis

Vomiting blood.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
MelaenaAlso: Melena

Black, tar-like stool caused by digested blood, usually from upper gastrointestinal bleeding.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
HaematocheziaAlso: Hematochezia

Passage of fresh red or maroon blood from the rectum.

Open definition page →
Constipation

Infrequent, difficult or incomplete bowel movements, often with hard stool.

Open definition page →
DiarrhoeaAlso: Diarrhea

Loose or watery stools occurring more often than usual.

Open definition page →
Irritable bowel syndromeAlso: IBS

A disorder of gut–brain interaction causing recurrent abdominal pain associated with altered bowel habits.

Open definition page →
Inflammatory bowel diseaseAlso: IBD

A group of chronic inflammatory bowel diseases, mainly Crohn disease and ulcerative colitis.

Open definition page →
Crohn disease

A chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract.

Open definition page →
Ulcerative colitis

A chronic inflammatory bowel disease involving the colon, usually beginning in the rectum.

Open definition page →
Diverticulosis

Presence of small outpouchings in the wall of the colon.

Open definition page →
Diverticulitis

Inflammation or infection involving one or more diverticula in the colon.

Open definition page →
Coeliac diseaseAlso: Celiac disease

An autoimmune condition triggered by gluten in genetically susceptible people, causing small-intestinal injury.

Open definition page →
Lactose intolerance

Reduced ability to digest lactose, often causing bloating, gas and diarrhoea.

Open definition page →
GallstoneAlso: Cholelithiasis

A solid deposit formed in the gallbladder.

Open definition page →
Cholecystitis

Inflammation of the gallbladder, commonly caused by a gallstone blocking the cystic duct.

Open definition page →
Biliary colic

Episodic upper abdominal pain caused when a gallstone temporarily obstructs bile flow.

Open definition page →
Common bile duct stoneAlso: Choledocholithiasis

A gallstone located in the main bile duct.

Open definition page →
Cholangitis

Infection and inflammation of the bile ducts, often due to obstruction.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Pancreatitis

Inflammation of the pancreas. Causes include gallstones, alcohol, very high triglycerides and some medicines.

Open definition page →
Appendicitis

Inflammation of the appendix, usually causing progressive abdominal pain and requiring prompt assessment.

Open definition page →
Peritonitis

Inflammation of the lining of the abdominal cavity, often due to infection or leakage from an abdominal organ.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Ascites

Abnormal accumulation of fluid inside the abdominal cavity.

Open definition page →
Hepatomegaly

Enlargement of the liver.

Open definition page →
Splenomegaly

Enlargement of the spleen.

Open definition page →
Portal hypertension

Abnormally high pressure in the portal venous system, most commonly due to cirrhosis.

Open definition page →
Oesophageal varicesAlso: Esophageal varices

Enlarged veins in the oesophagus caused by portal hypertension that can bleed severely.

Open definition page →
Hepatic encephalopathy

Brain dysfunction caused by severe liver failure or portal-systemic shunting, leading to confusion and altered consciousness.

Open definition page →
Colonoscopy

Examination of the colon with a flexible camera inserted through the rectum.

Open definition page →
GastroscopyAlso: Upper endoscopy · OGD

Examination of the oesophagus, stomach and duodenum with a flexible camera passed through the mouth.

Open definition page →

Respiratory

Breathing symptoms, asthma, COPD, infection, sleep apnoea and lung-function testing.

27 terms
DyspnoeaAlso: Dyspnea · Shortness of breath

The sensation of difficult or uncomfortable breathing.

Open definition page →
Hypoxia

Insufficient oxygen reaching body tissues.

Open definition page →
HypoxaemiaAlso: Hypoxemia

Lower-than-normal oxygen concentration in arterial blood.

Open definition page →
Oxygen saturationAlso: SpO2

The percentage of haemoglobin carrying oxygen, commonly estimated by a pulse oximeter.

Open definition page →
Asthma

A chronic inflammatory airway disease causing variable wheeze, cough, chest tightness and breathlessness.

Open definition page →
COPDAlso: Chronic obstructive pulmonary disease

A chronic lung disease with persistent airflow limitation, most often related to long-term smoking exposure.

Open definition page →
Emphysema

Destruction and enlargement of small air spaces in the lungs, reducing effective gas exchange.

Open definition page →
Chronic bronchitis

A clinical pattern of chronic productive cough, commonly associated with smoking and COPD.

Open definition page →
Bronchitis

Inflammation of the large airways. Acute bronchitis is commonly viral.

Open definition page →
Pneumonia

Infection of lung tissue causing inflammation and filling of air spaces.

Open definition page →
PleurisyAlso: Pleuritis

Inflammation of the membranes around the lungs, often causing sharp pain that worsens with breathing.

Open definition page →
Pleural effusion

Abnormal fluid collecting between the lung and chest wall.

Open definition page →
PneumothoraxAlso: Collapsed lung

Air in the pleural space causing partial or complete lung collapse.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Pulmonary oedemaAlso: Pulmonary edema

Fluid accumulation in the lungs, often due to heart failure but also caused by other conditions.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Sleep apnoeaAlso: Sleep apnea

Repeated episodes in which breathing stops or becomes markedly reduced during sleep.

Open definition page →
Obstructive sleep apnoeaAlso: OSA

Sleep apnoea caused by repeated collapse of the upper airway during sleep.

Open definition page →
CPAP

A machine that provides continuous positive airway pressure through a mask to keep the airway open during sleep.

Open definition page →
Spirometry

A breathing test measuring how much air a person can exhale and how quickly.

Open definition page →
FEV1

The amount of air forcefully exhaled in the first second of a spirometry manoeuvre.

Open definition page →
FVCAlso: Forced vital capacity

The total amount of air forcefully exhaled after taking the deepest possible breath.

Open definition page →
Bronchodilator

A medicine that relaxes airway smooth muscle and makes breathing easier.

Open definition page →
Inhaled corticosteroidAlso: ICS

An anti-inflammatory medicine delivered into the airways, commonly used for asthma.

Open definition page →
NebuliserAlso: Nebulizer

A device that converts liquid medication into a fine mist that can be inhaled.

Open definition page →
TuberculosisAlso: TB

An infection caused by Mycobacterium tuberculosis, most commonly affecting the lungs.

Open definition page →
Latent tuberculosis infectionAlso: LTBI

A state in which TB bacteria are present but controlled by the immune system, without contagious active disease.

Open definition page →
Pulmonary function testsAlso: PFTs

A group of tests assessing airflow, lung volumes and sometimes gas transfer.

Open definition page →
Peak flow

A simple measure of the maximum speed of forced expiration, often used in asthma monitoring.

Open definition page →

Neurology

Stroke, seizures, neuropathy, migraine, dementia and nervous-system terminology.

33 terms
StrokeAlso: Cerebrovascular accident · CVA

Sudden brain injury caused by interruption of blood supply or bleeding in the brain.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Ischaemic strokeAlso: Ischemic stroke

Stroke caused by blockage of an artery supplying the brain.

Open definition page →
Haemorrhagic strokeAlso: Hemorrhagic stroke

Stroke caused by bleeding into or around the brain.

Open definition page →
TIAAlso: Transient ischaemic attack · Mini-stroke

Temporary neurological symptoms caused by transient loss of blood flow to part of the brain.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Seizure

A sudden episode of abnormal electrical activity in the brain that can alter movement, awareness, sensation or behaviour.

Open definition page →
Epilepsy

A neurological condition characterised by a tendency to have recurrent unprovoked seizures.

Open definition page →
Status epilepticus

A prolonged seizure or repeated seizures without adequate recovery, requiring urgent treatment.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
SyncopeAlso: Fainting

A brief loss of consciousness caused by temporary reduction in blood flow to the brain, followed by spontaneous recovery.

Open definition page →
Vertigo

The sensation that you or the environment is spinning or moving when it is not.

Open definition page →
Dizziness

A broad symptom that may describe light-headedness, imbalance, vertigo or a feeling of impending faint.

Open definition page →
Migraine

A neurological disorder causing recurrent headache attacks, often with nausea, light sensitivity and sometimes aura.

Open definition page →
Aura

A temporary neurological symptom that can occur before or during some migraines or seizures.

Open definition page →
Neuropathy

Damage or dysfunction of nerves outside the brain and spinal cord, often causing numbness, tingling, pain or weakness.

Open definition page →
Peripheral neuropathy

Neuropathy affecting peripheral nerves, commonly beginning in the hands or feet.

Open definition page →
Radiculopathy

Symptoms caused by irritation or compression of a spinal nerve root.

Open definition page →
Sciatica

Pain radiating along the sciatic nerve pathway, usually from lower-back nerve-root irritation.

Open definition page →
ParaesthesiaAlso: Paresthesia

Abnormal skin sensations such as pins-and-needles, tingling or burning.

Open definition page →
Ataxia

Poor coordination or balance caused by dysfunction of the nervous system.

Open definition page →
Tremor

Involuntary rhythmic shaking of a body part.

Open definition page →
Parkinson disease

A progressive neurological disorder affecting movement and other brain functions, associated with loss of dopamine-producing neurons.

Open definition page →
Dementia

A syndrome of progressive cognitive decline severe enough to interfere with independent daily functioning.

Open definition page →
Alzheimer disease

The most common cause of dementia, associated with progressive impairment of memory and other cognitive functions.

Open definition page →
Delirium

An acute, fluctuating disturbance of attention and thinking, usually caused by an underlying medical problem, medicine or substance.

Useful context: New delirium often requires prompt medical evaluation.
Open definition page →
Multiple sclerosisAlso: MS

An immune-mediated disease in which inflammation damages myelin in the central nervous system.

Open definition page →
Meningitis

Inflammation of the membranes surrounding the brain and spinal cord, commonly caused by infection.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Encephalitis

Inflammation of brain tissue, often due to infection or autoimmune disease.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Aphasia

Impaired ability to understand or produce language because of brain dysfunction.

Open definition page →
Dysarthria

Difficulty speaking clearly because the muscles used for speech are weak or poorly coordinated.

Open definition page →
Hemiparesis

Weakness affecting one side of the body.

Open definition page →
Paralysis

Loss of voluntary muscle movement in part of the body.

Open definition page →
Neuralgia

Pain arising from irritation or damage to a nerve.

Open definition page →
EEGAlso: Electroencephalogram

A test that records electrical activity of the brain using scalp electrodes.

Open definition page →
Lumbar punctureAlso: Spinal tap

A procedure in which a needle is inserted into the lower back to collect cerebrospinal fluid or measure pressure.

Open definition page →

Mental Health & Substance Use

Anxiety, depression, psychosis, sleep, dependence, withdrawal and overdose language.

34 terms
Anxiety

A state of apprehension or fear that can become a disorder when persistent, excessive and impairing.

Open definition page →
Generalised anxiety disorderAlso: GAD

Persistent excessive worry about multiple areas of life that is difficult to control.

Open definition page →
Panic attack

A sudden surge of intense fear or discomfort with symptoms such as palpitations, breathlessness, chest tightness or dizziness.

Open definition page →
Panic disorder

Recurrent unexpected panic attacks together with persistent concern or behavioural change related to further attacks.

Open definition page →
Depression

A mental health condition involving persistent low mood or loss of interest together with changes in energy, sleep, appetite and functioning.

Open definition page →
Major depressive disorderAlso: MDD

A clinical depressive illness meeting defined criteria for severity, duration and functional impact.

Open definition page →
Bipolar disorder

A mood disorder characterised by episodes of depression and episodes of mania or hypomania.

Open definition page →
Mania

A period of abnormally elevated or irritable mood with increased energy, reduced need for sleep and major behavioural change.

Open definition page →
Hypomania

A milder form of elevated or irritable mood and increased energy that is less severe than mania.

Open definition page →
Psychosis

Loss of contact with reality, which may include hallucinations, delusions or severely disorganised thinking.

Open definition page →
Hallucination

A perception such as hearing or seeing something without an external stimulus.

Open definition page →
Delusion

A fixed false belief maintained despite strong evidence to the contrary and not explained by cultural context.

Open definition page →
Schizophrenia

A chronic psychiatric disorder that can involve psychosis, cognitive difficulties and functional impairment.

Open definition page →
Obsessive-compulsive disorderAlso: OCD

A condition involving intrusive unwanted thoughts and repetitive behaviours or mental rituals performed to reduce distress.

Open definition page →
Post-traumatic stress disorderAlso: PTSD

A trauma-related disorder that can include intrusive memories, avoidance and heightened arousal.

Open definition page →
ADHDAlso: Attention-deficit/hyperactivity disorder

A neurodevelopmental condition involving persistent inattention and/or hyperactivity-impulsivity that affects daily functioning.

Open definition page →
Autism spectrum disorderAlso: ASD · Autism

A neurodevelopmental condition involving differences in social communication and patterns of behaviour, interests or sensory processing.

Open definition page →
Insomnia

Persistent difficulty falling asleep, staying asleep or obtaining restorative sleep despite adequate opportunity.

Open definition page →
Dependence

A state in which the body adapts to a substance and stopping it may produce withdrawal. It is not identical to addiction.

Open definition page →
Addiction

A substance-use or behavioural disorder characterised by impaired control, craving and continued use despite harm.

Open definition page →
Tolerance

A state in which a larger dose is needed to achieve an effect previously produced by a smaller dose.

Open definition page →
Withdrawal

Physical or psychological symptoms that occur when a substance is reduced or stopped after adaptation.

Open definition page →
Alcohol withdrawal

Symptoms after abrupt reduction of heavy or dependent alcohol use, ranging from tremor to seizures or delirium.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Delirium tremensAlso: DTs

A severe form of alcohol withdrawal with confusion, agitation and autonomic overactivity.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Opioid

A class of medicines and drugs acting on opioid receptors, including morphine, oxycodone, fentanyl and heroin.

Open definition page →
Naloxone

A medicine that rapidly reverses opioid effects and can restore breathing during an opioid overdose.

Open definition page →
Overdose

Exposure to a drug or substance at a level that causes serious toxic effects.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
BenzodiazepineAlso: BZD

A class of sedative medicines used for selected conditions such as acute anxiety, seizures or muscle spasm.

Open definition page →
Antidepressant

A medicine used to treat depression and several anxiety-related conditions.

Open definition page →
Antipsychotic

A medicine used primarily to treat psychosis, mania and some other psychiatric conditions.

Open definition page →
Psychotherapy

Structured psychological treatment using evidence-based talking and behavioural approaches.

Open definition page →
Cognitive behavioural therapyAlso: CBT

A form of psychotherapy focusing on links between thoughts, emotions and behaviours.

Open definition page →
Suicidal ideation

Thoughts about suicide or ending one's life.

Useful context: Active suicidal intent, a plan or immediate risk requires urgent professional help.
⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Self-harm

Deliberate injury to oneself, with or without suicidal intent.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →

Infection, Immunity & Autoimmune Disease

Microbiology, allergy, autoimmunity and targeted immune treatments.

43 terms
Infection

Invasion and multiplication of microorganisms in the body, with or without symptoms.

Open definition page →
Bacterial infection

An infection caused by bacteria.

Open definition page →
Viral infection

An infection caused by a virus.

Open definition page →
Fungal infection

An infection caused by fungi such as yeasts or moulds.

Open definition page →
Parasitic infection

An infection caused by parasites such as protozoa or worms.

Open definition page →
Pathogen

A microorganism or infectious agent capable of causing disease.

Open definition page →
ColonisationAlso: Colonization

Presence of microorganisms on or in the body without causing tissue invasion or illness.

Open definition page →
Contagious

Able to spread from one person to another, directly or indirectly.

Open definition page →
Incubation period

The time between exposure to an infectious agent and development of symptoms.

Open definition page →
Sepsis

Life-threatening organ dysfunction caused by a dysregulated response to infection.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Septic shock

A severe form of sepsis with profound circulatory and metabolic abnormalities.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
BacteraemiaAlso: Bacteremia

Presence of bacteria in the bloodstream.

Open definition page →
ViraemiaAlso: Viremia

Presence of virus in the bloodstream.

Open definition page →
Culture

A laboratory method that allows microorganisms from a specimen to grow so they can be identified.

Open definition page →
Sensitivity testingAlso: Susceptibility testing

Testing that determines which antimicrobial medicines are likely to work against a microorganism.

Open definition page →
Antibiotic resistance

The ability of bacteria to survive or grow despite an antibiotic that would normally inhibit them.

Open definition page →
PCRAlso: Polymerase chain reaction

A molecular laboratory technique that detects specific genetic material.

Open definition page →
Antigen

A substance recognised by the immune system, often part of a microorganism or toxin.

Open definition page →
AntibodyAlso: Immunoglobulin

A protein produced by B cells that recognises a specific antigen.

Open definition page →
Serology

Blood testing that looks for antibodies, antigens or other markers of infection or immunity.

Open definition page →
Immunity

The body's ability to recognise and defend against specific threats.

Open definition page →
Innate immunity

Rapid, non-specific immune defence present from birth.

Open definition page →
Adaptive immunity

Specific immune responses that develop after exposure and can create immunological memory.

Open definition page →
Autoimmune disease

A disease in which the immune system mistakenly attacks the body's own tissues.

Open definition page →
Immunosuppression

Reduced immune-system activity caused by disease or medication.

Open definition page →
Immunodeficiency

A state in which part of the immune system is absent or does not function adequately.

Open definition page →
Allergy

An immune reaction to a substance that is usually harmless to most people.

Open definition page →
Anaphylaxis

A severe, rapidly developing systemic allergic reaction that can affect breathing and circulation.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
UrticariaAlso: Hives

Raised itchy wheals on the skin, commonly called hives.

Open definition page →
Angioedema

Deeper swelling beneath the skin, often affecting lips, eyelids or tongue.

Useful context: Airway involvement can be dangerous.
⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Rheumatoid arthritisAlso: RA

A chronic autoimmune inflammatory disease that primarily attacks joints and can affect other organs.

Open definition page →
Systemic lupus erythematosusAlso: SLE · Lupus

An autoimmune disease that can affect skin, joints, kidneys, blood cells, nervous system and other organs.

Open definition page →
Psoriatic arthritis

Inflammatory arthritis associated with psoriasis.

Open definition page →
Ankylosing spondylitisAlso: Axial spondyloarthritis

A chronic inflammatory disease primarily affecting the spine and sacroiliac joints.

Open definition page →
Sjögren syndromeAlso: Sjogren syndrome

An autoimmune disorder commonly causing dry eyes and dry mouth and sometimes systemic disease.

Open definition page →
Vasculitis

Inflammation of blood-vessel walls that can reduce blood flow and damage organs.

Open definition page →
ANAAlso: Antinuclear antibody

A group of autoantibodies directed against cell nuclei. A positive ANA is not by itself a diagnosis.

Open definition page →
Rheumatoid factorAlso: RF

An antibody that can be present in rheumatoid arthritis but also occurs in other conditions and some healthy people.

Open definition page →
Anti-CCP antibodyAlso: ACPA

An antibody strongly associated with rheumatoid arthritis and useful in diagnosis.

Open definition page →
Complement

A group of immune proteins that help antibodies and immune cells clear pathogens and damaged cells.

Open definition page →
Biologic medicineAlso: Biologic therapy

A treatment produced using biological systems, often designed to block a specific immune or inflammatory pathway.

Open definition page →
JAK inhibitor

A targeted medicine that blocks Janus kinase signalling, used in several inflammatory and blood disorders.

Open definition page →
Monoclonal antibody

A laboratory-produced antibody designed to bind a specific biological target.

Open definition page →

Vaccination & Travel Medicine

Vaccines, immunity, malaria, rabies, travel health and outbreak terminology.

33 terms
Vaccine

A biological product that trains the immune system to recognise and respond to a specific infection or toxin.

Open definition page →
Vaccination

Administration of a vaccine to produce protection against disease.

Open definition page →
ImmunisationAlso: Immunization

The process by which a person becomes protected against an infection, often through vaccination.

Open definition page →
Primary vaccine series

The initial set of vaccine doses needed to establish protection.

Open definition page →
Booster dose

An additional vaccine dose given later to strengthen or restore protection.

Open definition page →
Live attenuated vaccine

A vaccine containing a weakened living microorganism, with special precautions in pregnancy and significant immunosuppression.

Open definition page →
Inactivated vaccine

A vaccine containing killed organisms or components that cannot reproduce in the body.

Open definition page →
mRNA vaccine

A vaccine that delivers messenger RNA instructions so cells briefly make an antigen that stimulates immunity.

Open definition page →
Conjugate vaccine

A vaccine in which a bacterial polysaccharide is linked to a protein to create a stronger immune response.

Open definition page →
Toxoid vaccine

A vaccine protecting against a bacterial toxin using an inactivated form of that toxin.

Open definition page →
Adjuvant

An ingredient added to some vaccines to strengthen or shape the immune response.

Open definition page →
Contraindication

A condition or circumstance in which a treatment or vaccine should not be used because risk is unacceptable.

Open definition page →
Precaution

A condition requiring individual clinical judgement before treatment or vaccination.

Open definition page →
Adverse event

Any medical event occurring after treatment or vaccination, whether or not the treatment caused it.

Open definition page →
Vaccine side effect

An unwanted effect reasonably attributable to a vaccine, such as injection-site pain or temporary fever.

Open definition page →
Herd immunity

Reduced spread of an infection when a sufficiently large proportion of a population is immune.

Open definition page →
Catch-up vaccination

Vaccination given to bring someone up to date after missing routine doses.

Open definition page →
Seroconversion

Development of detectable antibodies after infection or vaccination.

Open definition page →
Vaccine efficacy

How well a vaccine reduces disease under controlled study conditions.

Open definition page →
Vaccine effectiveness

How well a vaccine works in real-world use.

Open definition page →
Travel vaccine

A vaccine recommended or required because of infection risks associated with travel.

Open definition page →
Yellow fever certificateAlso: International Certificate of Vaccination or Prophylaxis

Official proof of yellow fever vaccination used for specified international travel requirements.

Open definition page →
Malaria prophylaxisAlso: Antimalarial prophylaxis · Chemoprophylaxis

Medication taken before, during and after travel to reduce malaria risk.

Open definition page →
Traveller's diarrhoeaAlso: Traveler's diarrhea

Acute diarrhoea occurring during or shortly after travel, most often from contaminated food or water.

Open definition page →
Rabies post-exposure prophylaxisAlso: Rabies PEP

Urgent treatment after a possible rabies exposure, involving wound care, vaccine and sometimes rabies immunoglobulin.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Pre-exposure prophylaxisAlso: PrEP

Preventive treatment given before a possible future exposure.

Open definition page →
Endemic

Consistently present in a particular population or geographic area.

Open definition page →
Epidemic

Occurrence of disease above what is normally expected in a community or region.

Open definition page →
Pandemic

An epidemic that spreads across multiple countries or continents and affects large numbers of people.

Open definition page →
Vector

An organism, such as a mosquito or tick, that transmits an infectious agent between hosts.

Open definition page →
Vector-borne disease

An infection transmitted by organisms such as mosquitoes, ticks, fleas or sandflies.

Open definition page →
Altitude sicknessAlso: Acute mountain sickness

Illness caused by inadequate acclimatisation to high altitude.

Open definition page →
Jet lag

Temporary sleep and circadian disturbance after rapidly crossing multiple time zones.

Open definition page →

Cancer & Oncology

Cancer diagnosis, staging, biomarkers, treatment, trials and outcome terminology.

50 terms
Cancer

A group of diseases in which abnormal cells grow uncontrollably and can invade nearby tissue or spread elsewhere.

Open definition page →
TumourAlso: Tumor

An abnormal mass of tissue caused by excessive or abnormal cell growth. A tumour can be benign or malignant.

Open definition page →
Benign

Not cancerous. A benign growth does not invade or metastasise, although size or location can still cause problems.

Open definition page →
Malignant

Cancerous, with the ability to invade surrounding tissue and potentially spread to distant sites.

Open definition page →
Neoplasm

An abnormal new growth of tissue. Neoplasms can be benign, pre-malignant or malignant.

Open definition page →
Metastasis

Spread of cancer cells from the original site to another part of the body.

Open definition page →
Primary cancer

The organ or tissue where a cancer began.

Open definition page →
Secondary cancerAlso: Metastatic cancer

Cancer present in another site because it spread from the primary cancer.

Open definition page →
Carcinoma

Cancer arising from epithelial cells that line surfaces and organs.

Open definition page →
Adenocarcinoma

A carcinoma arising from gland-forming epithelial cells.

Open definition page →
Squamous cell carcinomaAlso: SCC

A cancer arising from squamous epithelial cells.

Open definition page →
Sarcoma

A cancer arising from connective or supporting tissues such as bone, muscle or fat.

Open definition page →
Lymphoma

A cancer arising from lymphocytes and lymphatic tissues.

Open definition page →
LeukaemiaAlso: Leukemia

A group of cancers involving blood-forming tissues and abnormal blood cells.

Open definition page →
Myeloma

A cancer of plasma cells, most commonly multiple myeloma.

Open definition page →
Biopsy

Removal of a tissue or cell sample for microscopic and sometimes molecular examination.

Open definition page →
Histology

Microscopic examination of tissue structure to diagnose disease.

Open definition page →
Cytology

Examination of individual cells or small groups of cells under a microscope.

Open definition page →
Pathology report

The formal laboratory report describing findings from tissue, cells or other specimens.

Open definition page →
Grade

A description of how abnormal cancer cells look and, in many cancers, how aggressively they may behave.

Open definition page →
Stage

A description of how far a cancer has spread in the body.

Open definition page →
TNM stagingAlso: TNM

A cancer-staging system describing the primary tumour, regional lymph nodes and distant metastasis.

Open definition page →
In situ

Abnormal or malignant cells confined to their original layer without invasion.

Open definition page →
Invasive cancer

Cancer that has grown beyond the tissue layer or structure where it first developed.

Open definition page →
Lymph node

A small immune-system structure that filters lymphatic fluid. Nodes can enlarge because of infection, inflammation or cancer.

Open definition page →
Remission

A period in which signs and symptoms of cancer are reduced or disappear. Remission is not always the same as cure.

Open definition page →
Complete responseAlso: Complete remission

Disappearance of all measurable evidence of cancer using the assessment methods being applied.

Open definition page →
Partial response

A substantial reduction in measurable tumour burden that does not meet criteria for complete response.

Open definition page →
Progression

Growth or spread of cancer despite or after treatment.

Open definition page →
Recurrence

Return of cancer after a period in which it was undetectable or controlled.

Open definition page →
Chemotherapy

Medicines that damage or kill rapidly dividing cells. Many regimens affect cancer cells and some normal cells.

Open definition page →
RadiotherapyAlso: Radiation therapy

Treatment using ionising radiation to damage cancer cells.

Open definition page →
Immunotherapy

Treatment that modifies or uses the immune system to attack cancer or other disease.

Open definition page →
Targeted therapy

Treatment designed to interfere with a specific molecule or pathway important to a cancer.

Open definition page →
Hormone therapy

Treatment that blocks or alters hormones that stimulate certain cancers.

Open definition page →
Checkpoint inhibitor

A cancer immunotherapy blocking inhibitory immune checkpoints such as PD-1, PD-L1 or CTLA-4.

Open definition page →
CAR-T therapy

Treatment in which a patient's T cells are genetically modified to recognise and attack a chosen target.

Open definition page →
Bispecific antibody

An engineered antibody designed to bind two different targets at the same time.

Open definition page →
Precision medicine

Use of molecular, genetic and clinical information to choose treatment or prevention more specifically.

Open definition page →
Biomarker

A measurable biological feature used to assess disease, risk, prognosis or treatment response.

Open definition page →
Tumour markerAlso: Tumor marker

A substance measured in blood or tissue that can sometimes help monitor or characterise a cancer. Most are not stand-alone screening tests.

Open definition page →
PSAAlso: Prostate-specific antigen

A prostate-produced protein measured in blood. It can rise with prostate cancer, benign enlargement and inflammation.

Open definition page →
CEAAlso: Carcinoembryonic antigen

A tumour marker mainly used to monitor selected colorectal and other cancers rather than diagnose cancer by itself.

Open definition page →
CA-125

A blood marker used mainly in evaluating and monitoring selected ovarian and other conditions. It is not specific for cancer.

Open definition page →
CA 19-9

A tumour marker used in selected pancreatic and biliary cancers but not sufficiently specific to diagnose cancer by itself.

Open definition page →
Minimal residual diseaseAlso: MRD

Very small numbers of cancer cells remaining after treatment that may be detectable only with sensitive tests.

Open definition page →
Progression-free survivalAlso: PFS

Time during and after treatment in which a patient remains alive without the cancer becoming measurably worse.

Open definition page →
Overall survivalAlso: OS

Time from a defined starting point until death from any cause.

Open definition page →
Objective response rateAlso: ORR

The proportion of study participants whose tumours shrink by a predefined amount.

Open definition page →
Clinical trial

A research study involving human participants that evaluates a medical intervention, diagnostic strategy or other health approach.

Open definition page →

Imaging, Ultrasound & Procedures

Ultrasound language, CT/MRI/X-ray terminology and common clinical procedures.

36 terms
UltrasoundAlso: Sonography

Imaging that uses high-frequency sound waves rather than ionising radiation to create pictures of internal structures.

Open definition page →
Doppler ultrasound

Ultrasound used to assess movement, particularly blood flow through vessels.

Open definition page →
Echogenicity

The degree to which tissue reflects ultrasound waves, determining how bright or dark it appears.

Open definition page →
Hyperechoic

Brighter than surrounding tissue on ultrasound because it reflects more sound.

Open definition page →
Hypoechoic

Darker than surrounding tissue on ultrasound because it reflects less sound.

Open definition page →
Anechoic

Completely or nearly black on ultrasound because there are few internal echoes, as often occurs with simple fluid.

Open definition page →
Lesion

A general term for an area of abnormal tissue. The word lesion does not by itself mean cancer.

Open definition page →
Mass

A discrete lump or area of tissue. A mass can have many benign or malignant causes.

Open definition page →
Nodule

A relatively small, rounded or defined area of tissue that differs from its surroundings.

Open definition page →
Cyst

A fluid-filled or partly fluid-filled sac. Many cysts are benign.

Open definition page →
Simple cyst

A cyst with typical benign imaging features such as clear fluid and a thin smooth wall.

Open definition page →
Complex cyst

A cystic lesion containing internal echoes, septa, solid areas or other features requiring closer assessment.

Open definition page →
Calcification

Deposit of calcium within tissue, visible on some imaging tests.

Open definition page →
Shadowing

A dark ultrasound area behind a structure that strongly blocks or reflects the sound beam, such as a gallstone.

Open definition page →
Acoustic enhancement

Increased brightness behind a fluid-filled structure because sound passes easily through fluid.

Open definition page →
CT scanAlso: Computed tomography

Cross-sectional imaging created with X-rays and computer processing.

Open definition page →
MRIAlso: Magnetic resonance imaging

Imaging using a strong magnetic field and radiofrequency signals rather than X-rays.

Open definition page →
X-ray

Imaging that uses ionising radiation to create pictures, particularly useful for bones and chest structures.

Open definition page →
Contrast agent

A substance given to make structures more visible on imaging.

Open definition page →
Radiopaque

Able to block X-rays and therefore appear relatively white on an X-ray image.

Open definition page →
Radiolucent

Allowing X-rays to pass through more easily, producing a darker appearance on X-ray.

Open definition page →
Incidental finding

An abnormality discovered unexpectedly during a test performed for another reason.

Open definition page →
Biopsy-guided imaging

Use of ultrasound, CT or other imaging to guide a needle accurately into a target.

Open definition page →
Endoscopy

Examination of an internal surface using a flexible or rigid instrument with a camera.

Open definition page →
Laparoscopy

Keyhole surgery performed through small abdominal incisions using a camera.

Open definition page →
Laparotomy

Open abdominal surgery through a larger incision.

Open definition page →
Local anaestheticAlso: Local anesthetic

Medicine that temporarily numbs a specific area while the patient remains conscious.

Open definition page →
General anaestheticAlso: General anesthetic

Medication-induced unconsciousness used for surgery or procedures.

Open definition page →
Sedation

Medication used to reduce anxiety and awareness during a procedure without necessarily causing full general anaesthesia.

Open definition page →
Catheter

A flexible tube inserted into the body to drain fluid, deliver treatment or access blood vessels.

Open definition page →
Cannula

A small tube inserted into a vein for fluids or medication, or into another body space for a specific procedure.

Open definition page →
IVAlso: Intravenous

A route directly into a vein.

Open definition page →
IM injectionAlso: Intramuscular injection

An injection delivered into muscle.

Open definition page →
Subcutaneous injectionAlso: SC injection

An injection delivered into the fatty tissue just beneath the skin.

Open definition page →
Sterile

Free from living microorganisms capable of causing contamination or infection.

Open definition page →
Aseptic technique

Methods used to minimise contamination by microorganisms during a procedure.

Open definition page →

Women's Health & Reproductive Medicine

Menstrual, fertility, pregnancy, pelvic ultrasound and menopause terminology.

30 terms
Menstrual cycle

The recurring hormonal cycle that prepares the ovaries and uterus for possible pregnancy.

Open definition page →
Menstruation

Shedding of the uterine lining, producing a menstrual period.

Open definition page →
AmenorrhoeaAlso: Amenorrhea

Absence of menstrual periods when they would normally be expected.

Open definition page →
DysmenorrhoeaAlso: Dysmenorrhea

Painful menstruation.

Open definition page →
MenorrhagiaAlso: Heavy menstrual bleeding

Menstrual bleeding that is unusually heavy or prolonged.

Open definition page →
Ovulation

Release of an egg from an ovary.

Open definition page →
Follicle

A fluid-filled ovarian structure containing a developing egg.

Open definition page →
Corpus luteum

The temporary ovarian structure formed after ovulation that produces progesterone.

Open definition page →
Endometrium

The inner lining of the uterus.

Open definition page →
Endometrial thickness

The measured thickness of the uterine lining, which changes with the menstrual cycle and hormonal state.

Open definition page →
FibroidAlso: Leiomyoma

A benign growth of uterine smooth muscle.

Open definition page →
Endometriosis

A condition in which tissue resembling the uterine lining grows outside the uterus, causing inflammation and sometimes pain or infertility.

Open definition page →
Adenomyosis

Growth of endometrial-type tissue within the muscular wall of the uterus.

Open definition page →
Ovarian cyst

A fluid-filled or partly fluid-filled structure in or on an ovary. Many are functional and resolve naturally.

Open definition page →
Polycystic ovary syndromeAlso: PCOS

A hormonal and metabolic condition commonly associated with irregular ovulation, androgen excess and polycystic ovarian morphology.

Open definition page →
Cervix

The lower part of the uterus that opens into the vagina.

Open definition page →
Pap smearAlso: Pap test · Cervical cytology

A screening test collecting cervical cells to look for changes associated with cervical-cancer risk.

Open definition page →
HPVAlso: Human papillomavirus

A group of viruses, some of which can cause genital warts and some of which increase the risk of cervical and other cancers.

Open definition page →
Colposcopy

Close examination of the cervix using magnification after an abnormal cervical screening result or other indication.

Open definition page →
Pregnancy testAlso: hCG test

A test that detects human chorionic gonadotropin, a hormone produced during pregnancy.

Open definition page →
hCGAlso: Human chorionic gonadotropin

A hormone produced mainly by placental tissue during pregnancy. Levels rise rapidly in early pregnancy.

Open definition page →
Gestational age

The age of a pregnancy counted from the first day of the last menstrual period.

Open definition page →
Ectopic pregnancy

A pregnancy implanted outside the main cavity of the uterus, most commonly in a fallopian tube.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Miscarriage

Loss of a pregnancy before fetal viability, usually in the first half of pregnancy.

Open definition page →
Placenta

The organ that develops during pregnancy to exchange oxygen, nutrients and waste products between mother and fetus.

Open definition page →
Menopause

The permanent end of menstrual periods due to loss of ovarian follicular activity.

Open definition page →
Perimenopause

The transition leading up to menopause, during which cycle timing and symptoms can change.

Open definition page →
HRTAlso: Hormone replacement therapy · Menopausal hormone therapy

Hormonal treatment used to relieve menopausal symptoms and for selected other indications.

Open definition page →
Transvaginal ultrasound

Pelvic ultrasound performed with a probe inserted gently into the vagina to obtain close views of the uterus and ovaries.

Open definition page →
Transabdominal pelvic ultrasound

Pelvic ultrasound performed through the lower abdomen, usually with a full bladder to improve the view.

Open definition page →

Musculoskeletal & Rheumatology

Bones, joints, tendons, arthritis, osteoporosis and common injuries.

29 terms
Arthritis

Inflammation or structural disease of a joint causing pain, swelling, stiffness or reduced movement.

Open definition page →
OsteoarthritisAlso: OA

A common joint disease involving cartilage loss and changes in bone and other joint tissues.

Open definition page →
Synovitis

Inflammation of the membrane lining a joint.

Open definition page →
Joint effusion

Excess fluid inside a joint.

Open definition page →
Bursitis

Inflammation of a bursa, a small fluid-filled sac that reduces friction near joints.

Open definition page →
TendinitisAlso: Tendonitis

Inflammation or irritation of a tendon.

Open definition page →
Tendinopathy

A broader term for tendon pain and structural change, often related to overload rather than acute inflammation alone.

Open definition page →
Ligament

A strong band of connective tissue connecting bone to bone.

Open definition page →
Tendon

Strong connective tissue that attaches muscle to bone.

Open definition page →
Sprain

Injury to a ligament, usually from stretching or tearing.

Open definition page →
Strain

Injury to muscle or tendon.

Open definition page →
Fracture

A break or crack in a bone.

Open definition page →
Stress fracture

A small bone fracture caused by repeated loading rather than a single major injury.

Open definition page →
Dislocation

Complete loss of normal contact between joint surfaces.

Open definition page →
Subluxation

Partial loss of normal joint alignment without complete dislocation.

Open definition page →
Meniscus

A crescent-shaped pad of fibrocartilage in the knee that helps distribute load and stabilise the joint.

Open definition page →
ACLAlso: Anterior cruciate ligament

A major knee ligament controlling forward and rotational movement of the tibia.

Open definition page →
Rotator cuff

A group of shoulder muscles and tendons that stabilise the shoulder and help lift and rotate the arm.

Open definition page →
Frozen shoulderAlso: Adhesive capsulitis

Painful progressive stiffness of the shoulder capsule.

Open definition page →
Carpal tunnel syndrome

Compression of the median nerve at the wrist, causing numbness, tingling and sometimes hand weakness.

Open definition page →
Gout

Inflammatory arthritis caused by deposition of monosodium urate crystals in joints.

Open definition page →
PseudogoutAlso: CPPD

Crystal arthritis caused mainly by calcium pyrophosphate deposition.

Open definition page →
Myalgia
Myositis

Inflammation of muscle.

Open definition page →
Rhabdomyolysis

Rapid breakdown of skeletal muscle releasing muscle-cell contents into the blood. Severe cases can cause kidney injury.

⚠ This term may describe a serious or urgent condition. Symptoms and context determine urgency.
Open definition page →
Bone density scanAlso: DEXA · DXA

A low-dose X-ray test that measures bone mineral density, commonly at the hip and spine.

Open definition page →
T-score

A bone-density comparison with the average peak bone density of a young healthy adult.

Open definition page →
Z-score

A bone-density comparison with people of the same age and sex.

Open definition page →
Fragility fracture

A fracture caused by a level of trauma that would not normally break healthy bone, often indicating osteoporosis.

Open definition page →

Skin & Dermatology

Inflammatory, infectious, pigmented and malignant skin terms.

20 terms
Dermatitis

Inflammation of the skin, commonly causing redness, itching and irritation.

Open definition page →
Eczema

A group of inflammatory skin conditions causing itch, dryness and rash.

Open definition page →
Psoriasis

A chronic immune-mediated skin disease causing well-defined scaly plaques and sometimes joint inflammation.

Open definition page →
Cellulitis

A bacterial infection of deeper skin and subcutaneous tissue causing redness, warmth, swelling and tenderness.

Open definition page →
Abscess

A collection of pus within tissue caused by infection.

Open definition page →
BoilAlso: Furuncle

A painful pus-filled infection of a hair follicle and surrounding tissue.

Open definition page →
MoleAlso: Naevus · Nevus

A usually benign collection of pigment-producing cells in the skin.

Open definition page →
Melanoma

A malignant tumour of melanocytes, the pigment-producing cells of skin and other tissues.

Open definition page →
Basal cell carcinomaAlso: BCC

A common skin cancer arising from basal cells. It usually grows locally and rarely metastasises.

Open definition page →
Squamous cell carcinoma of skin

A skin cancer arising from squamous cells that can invade and, in some cases, spread.

Open definition page →
Actinic keratosisAlso: Solar keratosis

A rough sun-damaged skin lesion that can sometimes progress to squamous cell carcinoma.

Open definition page →
Hidradenitis suppurativaAlso: HS

A chronic inflammatory skin disease causing painful nodules, abscesses and tunnels, mainly in skin folds.

Open definition page →
Alopecia

Hair loss from the scalp or body.

Open definition page →
Alopecia areata

An autoimmune condition causing well-defined patches of hair loss.

Open definition page →
Ulceration

Loss of the surface layer of skin or mucosa creating an open sore.

Open definition page →
Petechiae

Tiny non-blanching red or purple spots caused by small amounts of bleeding under the skin.

Open definition page →
Purpura

Purple or red skin discoloration caused by bleeding into the skin.

Open definition page →
Ecchymosis

A larger area of bleeding under the skin, commonly called a bruise.

Open definition page →
Pruritus
Erythema

Redness of the skin caused by increased blood flow.

Open definition page →

Medicines & Pharmacology

Medicine classes, doses, interactions, side effects and common prescribing language.

51 terms
Prescription medicine

A medicine that legally requires authorisation from an appropriately licensed prescriber.

Open definition page →
Over-the-counter medicineAlso: OTC

A medicine available without an individual prescription when used according to authorised conditions.

Open definition page →
Generic name

The standard non-brand name of a medicine based on its active ingredient.

Open definition page →
Brand name

The commercial name under which a medicine is marketed.

Open definition page →
Active ingredient

The substance in a medicine responsible for its therapeutic effect.

Open definition page →
Dose

The amount of medicine taken or administered at one time.

Open definition page →
Dosage regimen

The planned amount, timing, route and frequency of a medicine.

Open definition page →
Half-life

The time required for the amount of a medicine in the body or blood to fall by approximately half.

Open definition page →
Bioavailability

The proportion of a medicine dose that reaches systemic circulation in active form.

Open definition page →
Contraindicated

Describes a treatment that should not be used in a particular situation because risk outweighs expected benefit.

Open definition page →
Drug interaction

A change in a medicine's effect caused by another medicine, food, supplement, alcohol or substance.

Open definition page →
Side effect

An unwanted effect occurring at normal therapeutic doses.

Open definition page →
Adverse drug reactionAlso: ADR

A harmful or unintended response to a medicine used at normal doses.

Open definition page →
Allergic drug reaction

An immune-mediated reaction to a medicine, ranging from rash to anaphylaxis.

Open definition page →
Antibiotic

A medicine used to treat susceptible bacterial infections.

Open definition page →
Antiviral

A medicine that inhibits replication or effects of a virus.

Open definition page →
Antifungal

A medicine used to treat fungal infection.

Open definition page →
Antiparasitic

A medicine used to treat infections caused by parasites.

Open definition page →
AnalgesicAlso: Painkiller

A medicine used to reduce pain.

Open definition page →
ParacetamolAlso: Acetaminophen

A common analgesic and fever-reducing medicine. Excessive doses can cause serious liver injury.

Open definition page →
NSAIDAlso: Non-steroidal anti-inflammatory drug

A non-steroidal anti-inflammatory drug used for pain and inflammation, such as ibuprofen or naproxen.

Open definition page →
CorticosteroidAlso: Steroid

A medicine related to adrenal steroid hormones that strongly reduces inflammation and immune activity.

Open definition page →
Prednisolone

An oral corticosteroid used to treat many inflammatory and immune conditions.

Open definition page →
Antihistamine

A medicine blocking histamine effects, commonly used for allergies and itching.

Open definition page →
AnticoagulantAlso: Blood thinner

A medicine that reduces the blood's ability to form clots. It does not literally thin the blood.

Open definition page →
Antiplatelet

A medicine that reduces platelet activation and clot formation, such as aspirin or clopidogrel.

Open definition page →
Warfarin

An oral anticoagulant monitored using INR.

Open definition page →
DOACAlso: Direct oral anticoagulant

A direct oral anticoagulant such as apixaban, rivaroxaban, edoxaban or dabigatran.

Open definition page →
Statin

A medicine that lowers LDL cholesterol and reduces cardiovascular risk in appropriate patients.

Open definition page →
ACE inhibitorAlso: ACEi

A medicine used in hypertension, heart failure and kidney protection by blocking angiotensin-converting enzyme.

Open definition page →
ARBAlso: Angiotensin receptor blocker

A medicine blocking the angiotensin II receptor, used in hypertension and selected heart and kidney conditions.

Open definition page →
Beta blocker

A medicine that blocks beta-adrenergic receptors, slowing heart rate and reducing cardiac workload.

Open definition page →
Calcium-channel blockerAlso: CCB

A class used for hypertension, angina and some heart-rhythm conditions.

Open definition page →
DiureticAlso: Water tablet

A medicine that increases kidney excretion of sodium and water.

Open definition page →
Proton-pump inhibitorAlso: PPI

A medicine that strongly reduces stomach-acid production.

Open definition page →
Metformin

A common type 2 diabetes medicine that reduces liver glucose production and improves insulin sensitivity.

Open definition page →
GLP-1 receptor agonistAlso: GLP-1 RA

A medicine that mimics GLP-1 signalling to improve glucose regulation, reduce appetite and slow gastric emptying.

Open definition page →
SGLT2 inhibitorAlso: SGLT2i

A medicine that increases urinary glucose excretion and can provide heart and kidney benefits in selected patients.

Open definition page →
Insulin analogue

A modified form of insulin designed to have a particular onset and duration of action.

Open definition page →
SSRIAlso: Selective serotonin reuptake inhibitor

A common antidepressant class that increases serotonin signalling by blocking serotonin reuptake.

Open definition page →
SNRIAlso: Serotonin-noradrenaline reuptake inhibitor

An antidepressant class inhibiting serotonin and noradrenaline reuptake.

Open definition page →
AnticonvulsantAlso: Antiseizure medication

A medicine used to prevent seizures; some are also used for pain or mood disorders.

Open definition page →
Opioid analgesic

A pain medicine acting on opioid receptors. It can cause sedation, constipation, dependence and respiratory suppression.

Open definition page →
Antiemetic

A medicine used to prevent or treat nausea and vomiting.

Open definition page →
Laxative

A medicine used to treat constipation by changing stool consistency, bowel movement or both.

Open definition page →
Biologic

A medicine made using living systems, often a protein or antibody designed to act on a specific biological target.

Open definition page →
Biosimilar

A biological medicine shown to be highly similar to an authorised reference biologic without clinically meaningful differences.

Open definition page →
Taper

A planned gradual reduction in medicine dose rather than stopping suddenly.

Open definition page →
Discontinuation syndrome

Symptoms that can occur when certain medicines, especially some antidepressants, are stopped abruptly or reduced too quickly.

Open definition page →
Therapeutic drug monitoringAlso: TDM

Measuring blood concentrations of selected medicines to help keep exposure within a useful and safe range.

Open definition page →
Polypharmacy

Use of multiple medicines at the same time, especially when the number or complexity increases risk.

Open definition page →

General Clinical Terms & Symptoms

Words frequently found in reports, consultations and discharge letters.

54 terms
Acute

Beginning suddenly or lasting a relatively short period. Acute does not necessarily mean severe.

Open definition page →
Chronic

Persisting for a long period, often months or years.

Open definition page →
Subacute

Developing or lasting over an intermediate period between acute and chronic.

Open definition page →
Idiopathic

A condition for which no specific cause has been identified.

Open definition page →
Iatrogenic

Caused unintentionally by medical treatment or a healthcare intervention.

Open definition page →
Congenital

Present from birth, whether caused by genetics, development or another prenatal factor.

Open definition page →
Acquired

Developed after birth rather than present from birth.

Open definition page →
Hereditary

Passed through genetic inheritance from parent to child.

Open definition page →
Risk factor

A characteristic or exposure associated with a higher probability of developing a disease.

Open definition page →
Prognosis

The expected course or likely outcome of a disease.

Open definition page →
Diagnosis

Identification of a disease or condition based on symptoms, examination and tests.

Open definition page →
Differential diagnosis

The list of possible conditions that could explain a patient's symptoms or findings.

Open definition page →
Screening

Testing people without symptoms to identify disease or increased risk earlier.

Open definition page →
Sensitivity

In diagnostic testing, the ability of a test to correctly identify people who truly have the condition.

Open definition page →
Specificity

In diagnostic testing, the ability of a test to correctly identify people who do not have the condition.

Open definition page →
False positive

A test result suggesting disease when the disease is actually absent.

Open definition page →
False negative

A test result suggesting disease is absent when it is actually present.

Open definition page →
Positive predictive valueAlso: PPV

The probability that a person with a positive test result truly has the condition.

Open definition page →
Negative predictive valueAlso: NPV

The probability that a person with a negative test result truly does not have the condition.

Open definition page →
Symptom

A problem experienced and reported by the patient, such as pain or nausea.

Open definition page →
Sign

An objective finding observed or measured by a clinician, such as fever, rash or high blood pressure.

Open definition page →
Fever

A body temperature above the normal range, commonly related to infection or inflammation.

Open definition page →
Pyrexia

Another medical term for fever.

Open definition page →
Fatigue

A persistent sense of tiredness, low energy or reduced physical or mental capacity.

Open definition page →
Malaise

A general feeling of being unwell or lacking normal well-being.

Open definition page →
Pain

An unpleasant sensory and emotional experience associated with actual or potential tissue injury.

Open definition page →
Acute pain

Pain developing over a short period, often related to injury, inflammation or surgery.

Open definition page →
Chronic pain

Pain that persists or recurs for longer than expected for normal healing.

Open definition page →
OedemaAlso: Edema

Swelling caused by excess fluid in body tissues.

Open definition page →
Inflammation

The body's response to injury, infection or immune activation. Inflammation is not the same as infection.

Open definition page →
Dehydration

A deficit of body water, with or without loss of electrolytes.

Open definition page →
Nausea

The unpleasant sensation of feeling that vomiting may occur.

Open definition page →
VomitingAlso: Emesis

Forceful expulsion of stomach contents through the mouth.

Open definition page →
Anorexia

Loss of appetite. In clinical notes this term can mean reduced appetite and does not automatically mean anorexia nervosa.

Open definition page →
Cachexia

Complex loss of weight, muscle and strength associated with chronic disease.

Open definition page →
Cyanosis

Bluish or grey discoloration of skin or mucous membranes caused by abnormal oxygenation or circulation.

Open definition page →
Clubbing

Bulbous enlargement of the ends of fingers or toes, associated with several chronic conditions.

Open definition page →
Lymphadenopathy

Abnormal enlargement or change in lymph nodes.

Open definition page →
Organomegaly

Abnormal enlargement of an internal organ.

Open definition page →
TachypnoeaAlso: Tachypnea

Breathing faster than expected.

Open definition page →
Atrophy

Shrinkage or wasting of a tissue or organ.

Open definition page →
Hypertrophy

Increase in cell size causing enlargement of a tissue or organ.

Open definition page →
Hyperplasia

Increase in the number of cells within a tissue.

Open definition page →
Necrosis

Uncontrolled death of cells or tissue due to injury, loss of blood supply, toxins or severe inflammation.

Open definition page →
IschaemiaAlso: Ischemia

Insufficient blood supply to a tissue, reducing oxygen and nutrient delivery.

Open definition page →
Infarction

Death of tissue caused by prolonged loss of blood supply.

Open definition page →
Bilateral

Present on both sides of the body.

Open definition page →
Unilateral

Present on one side only.

Open definition page →
Proximal

Closer to the centre of the body or point of origin.

Open definition page →
Distal

Farther from the centre of the body or point of origin.

Open definition page →
Anterior

Toward the front of the body.

Open definition page →
Posterior

Toward the back of the body.

Open definition page →
Medial

Toward the midline of the body.

Open definition page →
Lateral

Away from the midline of the body.

Open definition page →

Medical Word Building

Prefixes, roots and suffixes that help decode unfamiliar medical words.

58 terms
cardio-

A common medical word part meaning “heart”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
neuro-

A common medical word part meaning “nervous system or nerves”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
hepato-

A common medical word part meaning “liver”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
nephro-

A common medical word part meaning “kidney”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
gastro-

A common medical word part meaning “stomach”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
entero-

A common medical word part meaning “intestine”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
colo-

A common medical word part meaning “colon”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
dermato-

A common medical word part meaning “skin”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
osteo-

A common medical word part meaning “bone”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
arthro-

A common medical word part meaning “joint”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
myo-

A common medical word part meaning “muscle”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
haemato-

A common medical word part meaning “blood”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
onco-

A common medical word part meaning “tumour or cancer”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
pneumo-

A common medical word part meaning “lung or air”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
thyro-

A common medical word part meaning “thyroid”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
glyco-

A common medical word part meaning “sugar or glucose”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
angio-

A common medical word part meaning “blood vessel”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
uro-

A common medical word part meaning “urinary tract”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
gynae-

A common medical word part meaning “female reproductive system”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
hystero-

A common medical word part meaning “uterus”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
cephalo-

A common medical word part meaning “head”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
encephalo-

A common medical word part meaning “brain”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
rhino-

A common medical word part meaning “nose”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
oto-

A common medical word part meaning “ear”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
ophthalmo-

A common medical word part meaning “eye”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-itis

A common medical word part meaning “inflammation”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-osis

A common medical word part meaning “a condition or process”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-oma

A common medical word part meaning “a tumour or mass”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-algia

A common medical word part meaning “pain”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-pathy

A common medical word part meaning “disease or disorder”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-megaly

A common medical word part meaning “enlargement”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-penia

A common medical word part meaning “too few or a reduced amount”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-cytosis

A common medical word part meaning “an increased number of cells”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-ectomy

A common medical word part meaning “surgical removal”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-otomy

A common medical word part meaning “cutting into or creating an incision”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-ostomy

A common medical word part meaning “surgically creating an opening”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-scopy

A common medical word part meaning “visual examination using a scope”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-gram

A common medical word part meaning “a record or image”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-graphy

A common medical word part meaning “the process of recording or imaging”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
-emia

A common medical word part meaning “a condition involving the blood”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
hyper-

A common medical word part meaning “above normal or excessive”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
hypo-

A common medical word part meaning “below normal or reduced”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
tachy-

A common medical word part meaning “fast”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
brady-

A common medical word part meaning “slow”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
dys-

A common medical word part meaning “abnormal, difficult or painful”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
a- / an-

A common medical word part meaning “without or absence of”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
peri-

A common medical word part meaning “around”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
endo-

A common medical word part meaning “inside or within”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
epi-

A common medical word part meaning “on, upon or above”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
sub-

A common medical word part meaning “under or below”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
intra-

A common medical word part meaning “within”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
inter-

A common medical word part meaning “between”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
trans-

A common medical word part meaning “across or through”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
poly-

A common medical word part meaning “many”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
oligo-

A common medical word part meaning “few or reduced”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
micro-

A common medical word part meaning “small”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
macro-

A common medical word part meaning “large”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →
neo-

A common medical word part meaning “new”. It can help decode unfamiliar terminology.

Useful context: The full medical word can have a more specific meaning than the word part alone.
Open definition page →

Common Abbreviations

Frequently seen shorthand in results, notes and prescriptions.

35 terms
BP

Blood pressure.

Open definition page →
HR
RR

Respiratory rate, meaning breaths per minute.

Open definition page →
Temp

Body temperature.

Open definition page →
SpO2

Peripheral oxygen saturation estimated by pulse oximetry.

Open definition page →
PRN

A medicine or treatment to be used when needed rather than on a fixed schedule.

Open definition page →
NPO

Nothing by mouth; no food or drink for a specified period.

Open definition page →
NBM
Hx
PMH

Past medical history.

Open definition page →
FH

Family history.

Open definition page →
SH

Social history.

Open definition page →
Dx
Tx
Rx

Prescription or treatment, depending on context.

Open definition page →
Bx
US
CXR
CT

Computed tomography.

Open definition page →
FBC

Full blood count.

Open definition page →
LFT

Liver function tests.

Open definition page →
U&E

Urea and electrolytes, a common kidney/electrolyte blood-test panel.

Open definition page →
Hb
WBC

White blood cell count.

Open definition page →
RBC

Red blood cell count.

Open definition page →
PLT

Platelet count.

Open definition page →
ANC

Absolute neutrophil count.

Open definition page →
GCS

Glasgow Coma Scale, a structured measure of consciousness.

Open definition page →
BMI

Body mass index.

Open definition page →
SC
PO

By mouth, from the Latin per os.

Open definition page →
SOB

Shortness of breath in many medical notes; context matters because abbreviations can be ambiguous.

Open definition page →
NAD

No abnormality detected in many clinical notes, though abbreviation usage varies.

Open definition page →
WNL

Within normal limits.

Open definition page →
NKDA

No known drug allergies.

Open definition page →
No matching term found.
Try a shorter word, a common abbreviation or the everyday name of the condition.
How Healthway writes definitions

Accurate enough to be useful. Simple enough to understand.

The dictionary preserves clinically important distinctions while avoiding unnecessary jargon.

Plain English first

Definitions start with what the word means, not with Latin, histology or molecular terminology.

Context matters

An abnormal result, lesion or imaging term is not interpreted as a diagnosis in isolation.

Trusted reference framework

Terminology is cross-checked against patient-facing resources from MedlinePlus/NLM, NCI and CDC.

CallWhatsAppBook