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Edition 28 Sep 202618 medical topicsOriginal sources linked
Autoimmune Diseases
3 articles · Newest source date first
Autoimmune Diseases ·
Oral TYK2–JAK1 inhibition produces broad improvement in dermatomyositis
The phase 3 VALOR trial found that brepocitinib improved muscle, skin and functional outcomes and allowed greater steroid reduction.
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Autoimmune Diseases ·
Obinutuzumab improves disease control in active systemic lupus erythematosus
The ALLEGORY trial provides phase 3 evidence that deeper B-cell depletion can improve global lupus disease activity when added to standard therapy.
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Autoimmune Diseases ·
Temporary mRNA CAR-T therapy points toward an outpatient 'immune reset' for myasthenia gravis
A BCMA-directed RNA CAR-T approach produced durable clinical effects without lymphodepletion in a small randomized study.
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