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33 articles · Newest source date first
Preclinical study in miceSemaglutide and ageing: promising mouse results need human testing
An experiment in older female mice found functional benefits and a longer lifespan.
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Observational health-record studyEndometriosis study highlights a possible link with type 2 diabetes
A large health-record analysis found an association that deserves further investigation.
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Preclinical and human-cell researchTau research links brain-cell damage to mitochondrial energy processes
Experiments identified a harmful feedback loop involving abnormal tau and cellular energy production.
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Clinical trialChildhood tooth decay: trial supports a topical approach to stopping progression
NIH highlighted evidence on silver diamine fluoride for cavities in young children.
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Long-term observational cohortMidlife heart and vascular health are linked to years lived without dementia
A decades-long study connects smoking, hypertension and diabetes with fewer dementia-free years.
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Phase III topline resultEnhertu meets Phase III PFS endpoint as first-line therapy for HER2-mutant advanced lung cancer
DESTINY-Lung04 met its primary progression-free survival endpoint versus platinum-pemetrexed chemotherapy plus pembrolizumab in previously untreated HER2-mutant advanced NSCLC.
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Randomized phase IINew oral nonpeptide GLP-1 VCT220 produces up to 9.7% mean weight loss at 16 weeks
One of the newest oral small-molecule GLP-1 candidates reported rapid weight loss and metabolic improvement in a 250-participant phase II trial.
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New iberdomide combination receives accelerated approval for previously treated multiple myeloma
The FDA has added a new oral CELMoD-based combination after a large randomized trial showed substantially deeper MRD-negative responses.
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Preclinical aging biologyAging stem cells may drive chronic inflammation through maladaptive 'trained immunity'
New work identifies loss of the mitochondrial regulator SIRT3 in hematopoietic stem cells as a potential upstream driver of inflammaging.
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