A growing collection.
Always here to read.
Explore every article we have published, from the latest edition to earlier discoveries. Search a subject, choose a topic or revisit a particular month.
All articles
33 articles · Newest source date first
FDA accelerated approvalOncolytic viral therapy plus nivolumab approved for advanced melanoma after PD-1 treatment
A genetically modified virus is now part of an FDA-approved immunotherapy strategy for a defined group of advanced melanoma patients.
Read article →
Phase 1 · 324 patientsFirst-in-class FcRH5×CD3 bispecific antibody shows activity in heavily pretreated myeloma
A fixed-duration cevostamab programme produced responses in a difficult late-line multiple myeloma population.
Read article →
Computational network medicineNetwork map of 2,358 longevity-linked genes identifies drug-repurposing candidates for aging biology
Researchers mapped the molecular hallmarks of aging onto the human protein interactome and screened thousands of compounds computationally.
Read article →
FDA expanded gene-therapy approvalCRISPR-based Casgevy expands to children from age two with sickle cell disease or transfusion-dependent β-thalassaemia
The age expansion brings gene-edited autologous stem-cell therapy to much younger children with severe inherited blood disorders.
Read article →
FDA accelerated approvalTzield becomes the first FDA-approved treatment aimed at preserving insulin production after recent stage 3 type 1 diabetes diagnosis in children
The anti-CD3 therapy now has a new indication intended to slow loss of endogenous insulin production in recently diagnosed pediatric type 1 diabetes.
Read article →
Oral aleniglipron reaches double-digit weight loss in phase 2b study
The small-molecule GLP-1 receptor agonist produced placebo-adjusted mean weight reductions up to 11.3% over 36 weeks.
Read article →
Randomized phase 2 proof-of-conceptCan weight-loss treatment preserve more muscle? Apitegromab study targets lean-mass loss during tirzepatide therapy
A myostatin-targeting antibody preserved more lean mass when combined with tirzepatide in a proof-of-concept obesity trial.
Read article →
Human calorie-restriction study identifies a possible molecular link to lower 'inflammaging'
Proteomic analysis of CALERIE participants suggests that modest long-term calorie restriction may dampen complement-related inflammatory signalling.
Read article →
First gene therapy approved for OTOF-associated inherited hearing loss
Otarmeni uses a dual-AAV system to deliver functional OTOF genetic material directly to inner-ear hair cells.
Read article →